C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GRB2-associated binding protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361507 GAB2-001 ENSG00000033327 9606 - 11:78215297-78417806 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361507
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361507 20.346±0.00 2.781±0.00 0.492±0.00 11.492±8.96 6.135±5.29 5.199±4.44 2.079±1.86 1.294±0.92 4.421±0.00 9.656±8.07 2.763±0.00 8.054±4.31 5.584±1.81 5.772±1.27

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005068 IDA transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005515 IPI protein binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007169 IDA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008284 IDA positive regulation of cell proliferation
GO:0016477 IEA cell migration
GO:0030316 IMP osteoclast differentiation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043306 ISS positive regulation of mast cell degranulation
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0045087 TAS innate immune response
GO:0048015 ISS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000004622 Gab2-201 protein_coding Mus_musculus 0 1624

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