C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium-sensing receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000036828 CASR 9606 + 3:122183683-122286503 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000490131 CASR-001 122183683-122285365 protein_coding
  ENST00000490186 CASR-003 122254331-122257638 retained_intron
  ENST00000498619 CASR-002 122184334-122286503 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonKidneyLiverLungOvaryTestisENST00000490131ENST00000498619
Transcript ID Adrenal Brain Breast Colon Kidney Liver Lung Ovary Testis
ENST00000490131 0.020±0.00 N/A 0.011±0.00 0.084±0.07 1.789±0.00 N/A 0.081±0.01 0.028±0.00 0.106±0.07
ENST00000498619 N/A 0.095±0.00 N/A N/A 5.554±0.00 0.050±0.00 N/A N/A 0.050±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001503 TAS ossification
GO:0002931 IEA response to ischemia
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005178 IEA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005513 TAS detection of calcium ion
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006816 IEA calcium ion transport
GO:0006874 TAS cellular calcium ion homeostasis
GO:0006915 IEA apoptotic process
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007254 IEA JNK cascade
GO:0007635 TAS chemosensory behavior
GO:0008144 IEA drug binding
GO:0008152 TAS metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0009653 TAS anatomical structure morphogenesis
GO:0009986 IEA cell surface
GO:0010038 IEA response to metal ion
GO:0010628 IEA positive regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019808 IEA polyamine binding
GO:0019901 IEA protein kinase binding
GO:0030424 IEA axon
GO:0032024 IEA positive regulation of insulin secretion
GO:0032781 IEA positive regulation of ATPase activity
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0042311 IEA vasodilation
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043679 IEA axon terminus
GO:0044325 IEA ion channel binding
GO:0045907 IEA positive regulation of vasoconstriction
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0051592 IEA response to calcium ion
GO:0051924 IEA regulation of calcium ion transport
GO:0060613 IEA fat pad development
GO:0070509 IDA calcium ion import
GO:0071305 IEA cellular response to vitamin D
GO:0071333 IEA cellular response to glucose stimulus
GO:0071404 IEA cellular response to low-density lipoprotein particle stimulus
GO:0071456 IEA cellular response to hypoxia
GO:0071774 IEA response to fibroblast growth factor
GO:0090280 IEA positive regulation of calcium ion import
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013649 CASR calcium-sensing receptor protein_coding Danio_rerio
ENSMUSG00000051980 Casr calcium-sensing receptor protein_coding Mus_musculus

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