C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium-sensing receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051980 Casr 10090 - 16:36493696-36562141 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063597 Casr-001 36493696-36562134 protein_coding
  ENSMUST00000114847 Casr-002 36493696-36562134 protein_coding
  ENSMUST00000172826 Casr-003 36494467-36561606 protein_coding
  ENSMUST00000174750 Casr-004 36517838-36562141 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063597ENSMUST00000114847ENSMUST00000172826
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063597 0.035±0.00 N/A N/A 0.076±0.00 N/A N/A 1.889±0.15 N/A N/A 0.279±0.11 N/A N/A N/A
ENSMUST00000114847 N/A N/A 0.012±0.00 0.012±0.00 0.395±0.00 N/A N/A 0.001±0.00 0.016±0.01 N/A 0.039±0.02 0.006±0.00 N/A
ENSMUST00000172826 0.027±0.01 0.012±0.00 0.004±0.00 0.031±0.04 0.492±0.01 0.057±0.02 3.693±0.87 0.003±0.00 0.034±0.02 0.301±0.07 0.034±0.02 0.011±0.00 0.795±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001503 IEA ossification
GO:0002931 IEA response to ischemia
GO:0005178 IEA integrin binding
GO:0005509 IEA calcium ion binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006816 IEA calcium ion transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006915 IEA apoptotic process
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007254 IEA JNK cascade
GO:0008144 IEA drug binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010038 IEA response to metal ion
GO:0010628 IDA positive regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019808 IEA polyamine binding
GO:0019901 IEA protein kinase binding
GO:0030424 IEA axon
GO:0032024 IEA positive regulation of insulin secretion
GO:0032781 IDA positive regulation of ATPase activity
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0042311 IEA vasodilation
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043679 IEA axon terminus
GO:0044325 IEA ion channel binding
GO:0045907 IEA positive regulation of vasoconstriction
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0050927 IEA positive regulation of positive chemotaxis
GO:0051592 IEA response to calcium ion
GO:0051924 IDA regulation of calcium ion transport
GO:0060613 IEA fat pad development
GO:0071305 IEA cellular response to vitamin D
GO:0071333 IEA cellular response to glucose stimulus
GO:0071404 IEA cellular response to low-density lipoprotein particle stimulus
GO:0071456 IEA cellular response to hypoxia
GO:0071774 IEA response to fibroblast growth factor
GO:0090280 IEA positive regulation of calcium ion import
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013649 CASR calcium-sensing receptor protein_coding Danio_rerio
ENSG00000036828 CASR calcium-sensing receptor protein_coding Homo_sapiens

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