C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adaptor-related protein complex 2, sigma 1 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000042753 AP2S1 9606 - 19:46838136-46850992 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263270 AP2S1-001 46838167-46850992 protein_coding
  ENST00000352203 AP2S1-007 46838136-46850777 protein_coding
  ENST00000593442 AP2S1-008 46838158-46850834 protein_coding
  ENST00000597020 AP2S1-002 46838172-46846148 protein_coding
  ENST00000597421 AP2S1-006 46845651-46850825 retained_intron
  ENST00000598027 AP2S1-009 46838446-46839656 retained_intron
  ENST00000599990 AP2S1-004 46838158-46850769 protein_coding
  ENST00000600964 AP2S1-010 46838172-46838820 retained_intron
  ENST00000601498 AP2S1-005 46838158-46850316 protein_coding
  ENST00000601649 AP2S1-003 46838447-46850766 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263270ENST00000597020ENST00000597421ENST00000598027ENST00000599990ENST00000600964ENST00000601498ENST00000601649
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263270 27.941±0.00 27.667±0.00 0.745±0.00 22.545±8.58 13.249±12.94 14.169±12.29 4.654±4.18 10.202±6.85 10.828±8.66 10.583±7.14 7.188±4.48 19.158±13.36 34.861±12.03 26.654±0.00
ENST00000597020 6.796±0.00 19.677±0.00 N/A 12.362±0.00 17.249±0.00 10.100±0.00 17.988±0.00 30.713±0.00 42.727±0.00 25.881±24.92 23.430±0.00 44.102±0.00 75.230±35.04 N/A
ENST00000597421 N/A N/A N/A N/A 1.904±0.00 N/A N/A 10.052±0.00 N/A N/A N/A 3.101±0.00 N/A N/A
ENST00000598027 N/A N/A 0.476±0.00 N/A N/A 5.868±0.00 1.993±0.00 6.754±0.00 N/A N/A 7.154±0.00 124.488±0.00 177.230±0.00 108.492±0.00
ENST00000599990 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.401±0.00
ENST00000600964 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 72.255±0.00 67.879±0.00 37.031±0.00
ENST00000601498 7.595±0.00 9.498±0.00 N/A N/A 0.347±0.00 0.368±0.00 N/A N/A N/A N/A N/A 1.529±0.00 N/A 11.201±0.00
ENST00000601649 N/A N/A N/A 13.153±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G1 CIL_0008G1_0001 VISTA 19:46806794-47408636

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 NAS transporter activity
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006810 IEA transport
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008565 IEA:NAS protein transporter activity
GO:0015031 IEA protein transport
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030100 TAS regulation of endocytosis
GO:0030122 TAS AP-2 adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048268 TAS clathrin coat assembly
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026967 ap2s1 adaptor-related protein complex 2, sigma 1 subunit protein_coding Danio_rerio
ENSMUSG00000008036 Ap2s1 adaptor-related protein complex 2, sigma 1 subunit protein_coding Mus_musculus

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