C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000044574 HSPA5 9606 - 9:125234853-125241330 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324460 HSPA5-001 125234853-125241330 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324460
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324460 44.190±0.00 77.023±0.00 11.835±0.00 15.759±11.42 38.329±7.97 87.723±66.80 21.652±14.59 128.562±101.79 77.133±66.76 105.323±91.79 12.987±11.29 95.408±64.05 163.078±21.57 117.826±12.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C6 CIL_0002C6_0002 CGP 9:125200542-125241330

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0001948 IPI glycoprotein binding
GO:0002576 TAS platelet degranulation
GO:0005509 TAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IMP nucleus
GO:0005739 IEA mitochondrion
GO:0005783 IMP endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006200 ISS ATP catabolic process
GO:0006983 IEA ER overload response
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007596 TAS blood coagulation
GO:0008180 IDA COP9 signalosome
GO:0009986 IEA cell surface
GO:0016020 IDA membrane
GO:0016887 ISS ATPase activity
GO:0019899 IPI enzyme binding
GO:0019904 IPI protein domain specific binding
GO:0021589 IEA cerebellum structural organization
GO:0021680 IEA cerebellar Purkinje cell layer development
GO:0021762 IEP substantia nigra development
GO:0030168 TAS platelet activation
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030335 IMP positive regulation of cell migration
GO:0030433 TAS ER-associated ubiquitin-dependent protein catabolic process
GO:0030496 IDA midbody
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0031625 IPI ubiquitin protein ligase binding
GO:0034663 IDA endoplasmic reticulum chaperone complex
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0035437 IMP maintenance of protein localization in endoplasmic reticulum
GO:0042149 IDA cellular response to glucose starvation
GO:0043022 IEA ribosome binding
GO:0043066 IMP negative regulation of apoptotic process
GO:0044267 TAS cellular protein metabolic process
GO:0051082 TAS unfolded protein binding
GO:0051087 TAS chaperone binding
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0051787 IDA misfolded protein binding
GO:0060904 TAS regulation of protein folding in endoplasmic reticulum
GO:0070062 IDA extracellular vesicular exosome
GO:0071236 IEA cellular response to antibiotic
GO:0071353 IEA cellular response to interleukin-4
GO:1901998 IEA toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004665 hspa5 heat shock protein 5 protein_coding Danio_rerio
ENSMUSG00000026864 Hspa5 heat shock protein 5 protein_coding Mus_musculus

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