C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026864 Hspa5 10090 + 2:34771970-34776531 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028222 Hspa5-002 34772092-34776531 protein_coding
  ENSMUST00000100171 Hspa5-001 34772095-34776531 protein_coding
  ENSMUST00000129333 Hspa5-008 34774847-34775615 processed_transcript
  ENSMUST00000137145 Hspa5-005 34772099-34773307 processed_transcript
  ENSMUST00000137505 Hspa5-004 34771970-34772710 processed_transcript
  ENSMUST00000145466 Hspa5-006 34772581-34774192 processed_transcript
  ENSMUST00000148308 Hspa5-003 34773200-34775735 processed_transcript
  ENSMUST00000155595 Hspa5-007 34773666-34774333 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028222ENSMUST00000100171ENSMUST00000137145ENSMUST00000137505ENSMUST00000155595
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028222 49.563±20.58 37.467±10.01 61.361±4.12 44.610±8.31 35.145±9.77 57.090±5.40 62.157±8.61 42.868±5.27 123.277±27.02 43.873±3.48 28.768±4.93 128.749±90.36 570.876±250.62 116.752±26.26
ENSMUST00000100171 22.746±1.06 40.996±6.48 13.893±5.74 29.545±6.09 28.075±5.08 31.470±6.98 11.137±0.00 15.754±4.74 32.942±5.12 24.695±5.84 9.189±1.60 77.211±27.50 155.124±7.59 24.838±0.00
ENSMUST00000137145 N/A 195.447±24.73 N/A N/A N/A 120.132±19.50 N/A 65.496±6.21 219.671±62.83 67.096±0.00 N/A 536.276±111.31 N/A N/A
ENSMUST00000137505 88.452±35.41 176.861±77.73 N/A 71.946±0.00 109.129±53.60 201.849±39.71 110.733±0.02 93.012±21.91 263.483±68.92 157.948±32.88 N/A 303.189±68.45 N/A 218.471±48.56
ENSMUST00000155595 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 263.442±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001948 IEA glycoprotein binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005783 IDA endoplasmic reticulum
GO:0005788 IDA endoplasmic reticulum lumen
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006983 IDA ER overload response
GO:0006987 IMP activation of signaling protein activity involved in unfolded protein response
GO:0008180 IEA COP9 signalosome
GO:0009986 IDA cell surface
GO:0016020 ISO membrane
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0021589 IMP cerebellum structural organization
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021762 IEA substantia nigra development
GO:0030176 IEA integral component of endoplasmic reticulum membrane
GO:0030335 ISS positive regulation of cell migration
GO:0030496 IEA midbody
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031398 IMP positive regulation of protein ubiquitination
GO:0031625 IEA ubiquitin protein ligase binding
GO:0034663 IEA endoplasmic reticulum chaperone complex
GO:0034976 ISO response to endoplasmic reticulum stress
GO:0035437 ISS maintenance of protein localization in endoplasmic reticulum
GO:0040019 TAS positive regulation of embryonic development
GO:0042149 IEA cellular response to glucose starvation
GO:0043022 IDA ribosome binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0051082 IEA unfolded protein binding
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0051787 IDA misfolded protein binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071236 IEA cellular response to antibiotic
GO:0071353 IDA cellular response to interleukin-4
GO:1901998 IMP toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004665 hspa5 heat shock protein 5 protein_coding Danio_rerio
ENSG00000044574 HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) protein_coding Homo_sapiens

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