C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000049192 ADAMTS6 9606 - 5:65148736-65481920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314351 ADAMTS6-006 65151528-65198765 processed_transcript
  ENST00000381052 ADAMTS6-008 65148739-65481417 nonsense_mediated_decay
  ENST00000381055 ADAMTS6-007 65148736-65481920 protein_coding
  ENST00000417396 ADAMTS6-012 65172940-65214183 processed_transcript
  ENST00000464680 ADAMTS6-009 65214645-65473691 retained_intron
  ENST00000470597 ADAMTS6-003 65214398-65473694 retained_intron
  ENST00000502886 ADAMTS6-010 65451316-65473673 retained_intron
  ENST00000504282 ADAMTS6-011 65256390-65262937 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314351ENST00000381052ENST00000381055ENST00000417396ENST00000464680ENST00000470597ENST00000502886
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314351 N/A N/A N/A 0.293±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000381052 N/A N/A N/A N/A 0.026±0.00 N/A 0.038±0.00 0.087±0.01 0.116±0.11 N/A 0.006±0.00 0.062±0.04 0.125±0.00 0.162±0.03
ENST00000381055 0.004±0.00 N/A N/A N/A N/A N/A 0.009±0.00 N/A N/A N/A N/A 0.350±0.00 0.127±0.04 0.228±0.09
ENST00000417396 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.745±0.00 N/A N/A 1.590±0.00
ENST00000464680 0.036±0.00 N/A N/A 0.102±0.07 0.044±0.00 0.076±0.05 0.252±0.00 N/A N/A 0.027±0.00 0.024±0.00 0.229±0.00 N/A 0.342±0.00
ENST00000470597 N/A 0.168±0.00 0.144±0.00 N/A 0.682±0.00 N/A N/A N/A N/A N/A N/A 0.045±0.00 N/A 0.437±0.00
ENST00000502886 N/A N/A 0.388±0.00 0.363±0.00 N/A 0.060±0.00 0.299±0.00 0.193±0.00 1.300±0.00 0.053±0.00 N/A 2.999±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007FW CIL_0007FW_0002 CGP 5:64768930-65481920

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008233 IEA peptidase activity
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0031012 IEA extracellular matrix

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041982 adamts6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 protein_coding Danio_rerio
ENSMUSG00000046169 Adamts6 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 protein_coding Mus_musculus

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