C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E receptor 3 (subtype EP3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000050628 PTGER3 9606 - 1:70852353-71047808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306666 PTGER3-005 70970781-71047788 protein_coding
  ENST00000351052 PTGER3-201 70974293-71047808 protein_coding
  ENST00000354608 PTGER3-202 70997159-71047808 protein_coding
  ENST00000356595 PTGER3-004 70952432-71047788 protein_coding
  ENST00000361210 PTGER3-002 70852442-71047808 nonsense_mediated_decay
  ENST00000370924 PTGER3-008 71006631-71047808 protein_coding
  ENST00000370931 PTGER3-006 70852353-71047788 protein_coding
  ENST00000370932 PTGER3-203 70852353-71047808 protein_coding
  ENST00000460330 PTGER3-007 70852573-71047633 protein_coding
  ENST00000479353 PTGER3-001 70852442-71047808 nonsense_mediated_decay
  ENST00000497146 PTGER3-003 70852442-71047788 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306666ENST00000351052ENST00000354608ENST00000370924ENST00000460330
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306666 11.722±0.00 0.662±0.00 N/A N/A 23.255±0.00 N/A 0.350±0.00 26.691±0.00 0.036±0.00 N/A 0.034±0.00 0.406±0.11 0.392±0.14 0.732±0.64
ENST00000351052 N/A N/A N/A N/A 2.491±0.00 N/A N/A N/A 0.048±0.00 N/A N/A 1.593±0.84 0.164±0.00 1.165±0.00
ENST00000354608 N/A N/A N/A N/A N/A N/A N/A N/A 0.192±0.00 N/A 0.184±0.00 N/A N/A N/A
ENST00000370924 6.544±0.00 0.254±0.00 2.036±0.00 0.495±0.31 6.355±4.21 1.354±0.18 0.249±0.01 12.050±0.00 2.574±0.00 0.500±0.11 0.059±0.05 0.455±0.18 0.186±0.10 0.623±0.60
ENST00000460330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.818±0.00 0.524±0.31 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004957 NAS prostaglandin E receptor activity
GO:0005515 IEA protein binding
GO:0005635 TAS nuclear envelope
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006351 TAS transcription, DNA-templated
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IEA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008150 ND biological_process
GO:0008219 TAS cell death
GO:0015701 IEA bicarbonate transport
GO:0016021 NAS:IEA integral component of membrane
GO:0030522 TAS intracellular receptor signaling pathway
GO:0031622 ISS positive regulation of fever generation
GO:0032496 IEA response to lipopolysaccharide
GO:0035810 IEA positive regulation of urine volume

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055781 ptger3 prostaglandin E receptor 3 (subtype EP3) protein_coding Danio_rerio
ENSMUSG00000040016 Ptger3 prostaglandin E receptor 3 (subtype EP3) protein_coding Mus_musculus

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