C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E receptor 3 (subtype EP3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040016 Ptger3 10090 + 3:157566892-157644758 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041175 Ptger3-001 157566892-157644758 protein_coding
  ENSMUST00000173533 Ptger3-002 157566900-157644756 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041175ENSMUST00000173533
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041175 20.173±2.28 27.823±16.70 0.552±0.09 0.144±0.09 32.300±17.58 8.153±2.39 0.499±0.40 9.015±5.66 0.334±0.19 0.642±0.12 0.172±0.10 5.720±2.59 3.551±0.54 0.053±0.04
ENSMUST00000173533 27.254±13.03 N/A 1.632±0.51 0.219±0.09 13.689±2.70 1.377±0.23 0.301±0.07 8.384±0.62 0.560±0.29 0.759±0.18 0.245±0.07 2.099±1.58 4.562±3.02 0.052±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005R6 CIL_0005R6_0002 CGP 3:157534160-157644758
CIL_0000WV CIL_0000WV_0002 CGP 3:157566892-157925077

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001660 IDA fever generation
GO:0004957 IMP prostaglandin E receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007188 IDA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007200 IDA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0015701 IMP bicarbonate transport
GO:0016021 IEA integral component of membrane
GO:0032496 IMP response to lipopolysaccharide
GO:0035810 IMP positive regulation of urine volume

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055781 ptger3 prostaglandin E receptor 3 (subtype EP3) protein_coding Danio_rerio
ENSG00000050628 PTGER3 prostaglandin E receptor 3 (subtype EP3) protein_coding Homo_sapiens

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