C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1, regulatory subunit 12A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000058272 PPP1R12A 9606 - 12:79773563-79935460 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261207 PPP1R12A-201 79773563-79935455 protein_coding
  ENST00000437004 PPP1R12A-002 79774406-79935460 protein_coding
  ENST00000450142 PPP1R12A-001 79773568-79935198 protein_coding
  ENST00000546369 PPP1R12A-005 79775923-79913911 protein_coding
  ENST00000546762 PPP1R12A-015 79775541-79797237 nonsense_mediated_decay
  ENST00000547131 PPP1R12A-011 79797330-79821118 protein_coding
  ENST00000547253 PPP1R12A-021 79775918-79782341 retained_intron
  ENST00000547330 PPP1R12A-003 79797234-79935130 protein_coding
  ENST00000548318 PPP1R12A-009 79828371-79872872 protein_coding
  ENST00000548908 PPP1R12A-006 79775931-79790485 retained_intron
  ENST00000550001 PPP1R12A-017 79806816-79809815 retained_intron
  ENST00000550007 PPP1R12A-018 79797269-79805816 retained_intron
  ENST00000550107 PPP1R12A-004 79775929-79934931 protein_coding
  ENST00000550299 PPP1R12A-019 79775918-79796790 protein_coding
  ENST00000550351 PPP1R12A-020 79775918-79786914 retained_intron
  ENST00000550369 PPP1R12A-016 79789797-79793873 retained_intron
  ENST00000550510 PPP1R12A-008 79821112-79934715 protein_coding
  ENST00000550903 PPP1R12A-014 79775914-79797254 nonsense_mediated_decay
  ENST00000551191 PPP1R12A-010 79828128-79832596 retained_intron
  ENST00000551781 PPP1R12A-013 79793797-79797398 retained_intron
  ENST00000552892 PPP1R12A-007 79775935-79780745 retained_intron
  ENST00000553081 PPP1R12A-012 79796917-79817443 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261207ENST00000450142ENST00000547330ENST00000550007ENST00000550107ENST00000550299ENST00000550510ENST00000550903ENST00000553081
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261207 11.060±0.00 10.555±0.00 2.566±0.00 5.571±2.17 10.269±3.35 11.165±3.37 1.996±0.24 3.859±0.00 19.067±18.68 8.287±0.23 N/A 6.515±2.16 5.570±1.00 8.221±1.06
ENST00000450142 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.682±0.00 0.829±0.00 4.393±0.00
ENST00000547330 N/A N/A 2.038±0.00 3.365±0.00 N/A 5.433±0.00 1.711±0.00 N/A N/A 8.131±0.00 1.288±0.00 N/A N/A N/A
ENST00000550007 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 36.220±0.00 52.036±0.00 77.590±0.00
ENST00000550107 N/A N/A 1.291±0.00 N/A N/A N/A N/A N/A N/A N/A 0.330±0.00 N/A 3.337±0.00 N/A
ENST00000550299 N/A N/A N/A N/A N/A 16.936±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000550510 N/A N/A N/A N/A N/A N/A 9.031±0.00 N/A N/A N/A 3.826±0.00 N/A N/A N/A
ENST00000550903 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.339±0.00 9.654±0.00 14.488±0.00
ENST00000553081 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.897±0.00 11.835±0.00 13.010±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BD CIL_0002BD_0002 CGP 12:79574979-79935460

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0004857 IDA enzyme inhibitor activity
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005925 IDA focal adhesion
GO:0006470 IMP protein dephosphorylation
GO:0007067 IMP mitotic nuclear division
GO:0007165 NAS signal transduction
GO:0015629 IDA actin cytoskeleton
GO:0019208 IMP phosphatase regulator activity
GO:0019901 IPI protein kinase binding
GO:0030155 IDA regulation of cell adhesion
GO:0035507 IDA regulation of myosin-light-chain-phosphatase activity
GO:0043086 IDA negative regulation of catalytic activity
GO:0043292 IDA contractile fiber
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046822 IEA regulation of nucleocytoplasmic transport
GO:0051297 IMP centrosome organization
GO:0071889 IDA 14-3-3 protein binding
GO:0072357 IDA PTW/PP1 phosphatase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010784 ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A protein_coding Danio_rerio
ENSMUSG00000019907 Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A protein_coding Mus_musculus

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