C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1, regulatory (inhibitor) subunit 12A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019907 Ppp1r12a 10090 + 10:108162400-108277575 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070663 Ppp1r12a-201 108162400-108277575 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070663
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070663 16.030±2.31 3.442±0.32 161.020±26.78 9.581±3.30 4.703±0.00 9.489±2.42 3.828±2.28 2.580±0.00 4.924±1.61 5.663±2.05 0.858±0.00 14.791±5.59 9.538±4.09 2.423±1.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000776 ISS kinetochore
GO:0004857 ISS enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0005925 IEA focal adhesion
GO:0006470 IMP protein dephosphorylation
GO:0007067 ISS mitotic nuclear division
GO:0015629 IEA actin cytoskeleton
GO:0019208 ISS phosphatase regulator activity
GO:0019901 IEA protein kinase binding
GO:0030155 ISS regulation of cell adhesion
GO:0035507 ISS regulation of myosin-light-chain-phosphatase activity
GO:0043086 ISS negative regulation of catalytic activity
GO:0043292 IEA contractile fiber
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046822 IMP regulation of nucleocytoplasmic transport
GO:0051297 ISS centrosome organization
GO:0071889 ISS 14-3-3 protein binding
GO:0072357 ISS PTW/PP1 phosphatase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010784 ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A protein_coding Danio_rerio
ENSG00000058272 PPP1R12A protein phosphatase 1, regulatory subunit 12A protein_coding Homo_sapiens

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