C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000063046 EIF4B 9606 + 12:53006158-53042209 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262056 EIF4B-001 53006158-53042209 protein_coding
  ENST00000416762 EIF4B-005 53006457-53040462 protein_coding
  ENST00000420463 EIF4B-007 53006456-53040280 protein_coding
  ENST00000549077 EIF4B-010 53006431-53027856 nonsense_mediated_decay
  ENST00000549481 EIF4B-015 53006468-53034619 protein_coding
  ENST00000549592 EIF4B-008 53037726-53040352 retained_intron
  ENST00000549645 EIF4B-017 53006448-53021835 processed_transcript
  ENST00000550025 EIF4B-011 53018860-53021916 retained_intron
  ENST00000550390 EIF4B-012 53006484-53027872 nonsense_mediated_decay
  ENST00000550704 EIF4B-013 53006459-53037434 nonsense_mediated_decay
  ENST00000551002 EIF4B-014 53006456-53022607 protein_coding
  ENST00000551527 EIF4B-009 53006282-53021758 processed_transcript
  ENST00000552490 EIF4B-016 53006469-53028173 protein_coding
  ENST00000553209 EIF4B-018 53034646-53037724 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262056ENST00000416762
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262056 158.408±0.00 22.117±0.00 26.503±4.02 39.485±0.96 93.777±56.62 30.524±2.11 38.844±6.30 38.528±30.30 77.094±33.05 70.324±40.53 117.598±83.77 56.851±8.51 45.477±0.00
ENST00000416762 N/A 41.258±0.00 34.137±0.00 56.676±0.00 43.099±0.00 45.213±0.00 62.794±0.00 97.661±0.00 52.620±0.00 30.046±0.00 61.834±23.69 46.162±0.00 37.282±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TF CIL_0006TF_0001 CGP 12:52948871-53042209
CIL_00033N CIL_00033N_0002 CGP 12:53006158-53064372

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003676 IEA nucleic acid binding
GO:0003723 TAS RNA binding
GO:0003743 IEA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0006446 TAS regulation of translational initiation
GO:0008286 TAS insulin receptor signaling pathway
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016281 TAS eukaryotic translation initiation factor 4F complex
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010194 eif4bb eukaryotic translation initiation factor 4Bb protein_coding Danio_rerio
ENSDARG00000017439 eif4ba eukaryotic translation initiation factor 4Ba protein_coding Danio_rerio
ENSMUSG00000058655 Eif4b eukaryotic translation initiation factor 4B protein_coding Mus_musculus

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