C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sphingosine kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000063176 SPHK2 9606 + 19:48619291-48630717 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245222 SPHK2-001 48619291-48630405 protein_coding
  ENST00000340932 SPHK2-201 48619291-48630406 protein_coding
  ENST00000426514 SPHK2-007 48620515-48629773 nonsense_mediated_decay
  ENST00000593308 SPHK2-013 48624428-48626175 protein_coding
  ENST00000597434 SPHK2-008 48624006-48630717 non_stop_decay
  ENST00000598088 SPHK2-005 48619534-48630405 protein_coding
  ENST00000598574 SPHK2-011 48625029-48626814 retained_intron
  ENST00000599029 SPHK2-010 48624969-48630717 protein_coding
  ENST00000599033 SPHK2-014 48624472-48626301 processed_transcript
  ENST00000599748 SPHK2-009 48624952-48630405 protein_coding
  ENST00000600537 SPHK2-004 48619452-48629916 protein_coding
  ENST00000601704 SPHK2-012 48624343-48626358 protein_coding
  ENST00000601712 SPHK2-003 48619450-48628651 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENST00000426514
Transcript ID Testis
ENST00000426514 36.555±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IEA blood vessel development
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005765 IDA lysosomal membrane
GO:0005829 IDA cytosol
GO:0006665 TAS sphingolipid metabolic process
GO:0006669 NAS sphinganine-1-phosphate biosynthetic process
GO:0006670 IEA sphingosine metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IEA brain development
GO:0008283 NAS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008481 NAS sphinganine kinase activity
GO:0016020 IDA membrane
GO:0016310 IEA phosphorylation
GO:0017016 NAS Ras GTPase binding
GO:0017050 IEA D-erythro-sphingosine kinase activity
GO:0030148 TAS sphingolipid biosynthetic process
GO:0043066 NAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0046834 IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069893 sphk2 sphingosine kinase 2 protein_coding Danio_rerio
ENSMUSG00000057342 Sphk2 sphingosine kinase 2 protein_coding Mus_musculus

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