C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sphingosine kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057342 Sphk2 10090 - 7:45709467-45718002 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072836 Sphk2-002 45710285-45715207 protein_coding
  ENSMUST00000107737 Sphk2-001 45709467-45718002 protein_coding
  ENSMUST00000107738 Sphk2-003 45710267-45717902 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072836ENSMUST00000107737ENSMUST00000107738
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072836 N/A N/A N/A 11.583±0.00 N/A 46.429±5.77 N/A N/A 16.457±4.68 12.881±0.00 N/A 16.603±1.25 N/A 9.073±0.32
ENSMUST00000107737 17.257±2.73 40.173±2.83 31.378±2.68 25.263±0.00 20.084±6.89 N/A 10.445±1.20 14.478±7.17 7.123±1.15 20.104±3.60 11.410±2.32 24.758±8.01 N/A 9.323±1.66
ENSMUST00000107738 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.862±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001568 IGI blood vessel development
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005765 IEA lysosomal membrane
GO:0005829 IDA cytosol
GO:0006669 NAS sphinganine-1-phosphate biosynthetic process
GO:0006670 IMP sphingosine metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IGI brain development
GO:0008283 NAS cell proliferation
GO:0008284 IGI positive regulation of cell proliferation
GO:0008481 NAS sphinganine kinase activity
GO:0016020 IDA membrane
GO:0017050 IDA D-erythro-sphingosine kinase activity
GO:0043066 NAS negative regulation of apoptotic process
GO:0046834 IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069893 sphk2 sphingosine kinase 2 protein_coding Danio_rerio
ENSG00000063176 SPHK2 sphingosine kinase 2 protein_coding Homo_sapiens

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