C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, theta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065675 PRKCQ 9606 - 10:6427143-6580301 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263125 PRKCQ-001 6427143-6580301 protein_coding
  ENST00000397176 PRKCQ-201 6427143-6580301 protein_coding
  ENST00000539722 PRKCQ-202 6427143-6580301 protein_coding
  ENST00000610727 PRKCQ-203 6427143-6512172 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263125ENST00000397176ENST00000539722ENST00000610727
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263125 N/A N/A 0.438±0.00 0.498±0.00 N/A N/A 2.081±0.00 N/A 0.959±0.00 16.220±9.17 0.304±0.05 N/A N/A
ENST00000397176 N/A N/A N/A N/A N/A 0.107±0.00 N/A N/A N/A N/A 0.043±0.00 0.024±0.00 N/A
ENST00000539722 0.082±0.00 N/A N/A N/A 0.673±0.00 0.091±0.00 N/A 0.037±0.00 1.466±0.00 N/A N/A N/A 0.173±0.01
ENST00000610727 N/A 2.199±0.00 0.395±0.00 2.242±0.31 0.568±0.19 N/A 0.709±0.69 0.060±0.00 0.461±0.00 9.813±0.00 0.314±0.22 0.145±0.13 1.207±0.14

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0001772 IEA immunological synapse
GO:0004672 IEA protein kinase activity
GO:0004674 NAS:IEA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0006954 IEA inflammatory response
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0016567 TAS protein ubiquitination
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0030168 TAS platelet activation
GO:0032740 ISS positive regulation of interleukin-17 production
GO:0032753 ISS positive regulation of interleukin-4 production
GO:0035556 NAS:IEA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042102 IEA positive regulation of T cell proliferation
GO:0045086 IEA positive regulation of interleukin-2 biosynthetic process
GO:0045087 TAS innate immune response
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0046872 IEA metal ion binding
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 ISS positive regulation of T cell activation
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0070233 IMP negative regulation of T cell apoptotic process
GO:0090330 ISS regulation of platelet aggregation
GO:2000318 ISS positive regulation of T-helper 17 type immune response
GO:2000570 ISS positive regulation of T-helper 2 cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034173 prkcq protein kinase C, theta protein_coding Danio_rerio
ENSMUSG00000026778 Prkcq protein kinase C, theta protein_coding Mus_musculus

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