C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, theta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026778 Prkcq 10090 + 2:11172113-11301226 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028118 Prkcq-001 11172382-11301226 protein_coding
  ENSMUST00000102970 Prkcq-002 11172310-11284369 protein_coding
  ENSMUST00000114853 Prkcq-003 11172113-11263085 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028118ENSMUST00000102970ENSMUST00000114853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028118 0.263±0.11 0.118±0.02 2.271±0.21 1.732±0.74 4.796±1.57 0.401±0.13 0.434±0.07 1.811±0.56 1.014±0.86 1.258±0.68 20.051±2.02 0.384±0.21 0.232±0.11 25.011±1.62
ENSMUST00000102970 N/A 0.310±0.08 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.820±0.00 N/A N/A
ENSMUST00000114853 0.303±0.14 0.319±0.14 0.481±0.02 0.799±0.17 1.848±1.73 0.554±0.24 0.208±0.05 0.444±0.10 0.298±0.11 0.521±0.11 N/A 0.627±0.32 0.388±0.08 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000QF CIL_0000QF_0002 CGP 2:10370510-11301226
CIL_0000QE CIL_0000QE_0002 CGP 2:11172113-11502101

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IDA immunological synapse
GO:0002376 IEA immune system process
GO:0004697 IDA protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0006954 IEA inflammatory response
GO:0032740 IMP positive regulation of interleukin-17 production
GO:0032753 IMP positive regulation of interleukin-4 production
GO:0035556 IMP intracellular signal transduction
GO:0042102 IMP positive regulation of T cell proliferation
GO:0045086 IMP positive regulation of interleukin-2 biosynthetic process
GO:0046627 ISS negative regulation of insulin receptor signaling pathway
GO:0046872 IEA metal ion binding
GO:0050870 IMP positive regulation of T cell activation
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0070233 ISS negative regulation of T cell apoptotic process
GO:0090330 IMP regulation of platelet aggregation
GO:2000318 IMP positive regulation of T-helper 17 type immune response
GO:2000570 IMP positive regulation of T-helper 2 cell activation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034173 prkcq protein kinase C, theta protein_coding Danio_rerio
ENSG00000065675 PRKCQ protein kinase C, theta protein_coding Homo_sapiens

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