C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit B', alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000066027 PPP2R5A 9606 + 1:212285537-212361863 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261461 PPP2R5A-001 212285537-212361863 protein_coding
  ENST00000479259 PPP2R5A-003 212301863-212342280 processed_transcript
  ENST00000498123 PPP2R5A-004 212301863-212319545 processed_transcript
  ENST00000498129 PPP2R5A-002 212301863-212342280 processed_transcript
  ENST00000537030 PPP2R5A-005 212301806-212360922 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261461ENST00000537030
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261461 20.631±0.00 14.319±0.00 2.145±0.00 5.379±1.51 20.930±16.81 8.579±6.24 12.128±8.59 12.195±8.38 10.603±5.91 17.530±9.61 9.090±0.00 8.888±4.39 12.934±0.72 7.371±1.36
ENST00000537030 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.641±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000129 CIL_000129_0002 CGP 1:212035553-212361863
CIL_0008JQ CIL_0008JQ_0001 VISTA 1:212231404-212833951

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000159 IDA:IEA protein phosphatase type 2A complex
GO:0000775 IEA chromosome, centromeric region
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0007165 IEA signal transduction
GO:0008601 IEA protein phosphatase type 2A regulator activity
GO:0016020 IDA membrane
GO:0019900 IPI kinase binding
GO:0030018 IEA Z disc
GO:0031430 ISS M band
GO:0035307 IMP positive regulation of protein dephosphorylation
GO:0090005 IMP negative regulation of establishment of protein localization to plasma membrane
GO:0090219 IMP negative regulation of lipid kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027017 ppp2r5a protein phosphatase 2, regulatory subunit B', alpha isoform protein_coding Danio_rerio
ENSMUSG00000026626 Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha protein_coding Mus_musculus

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