C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Na+/K+ transporting, beta 3 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000069849 ATP1B3 9606 + 3:141876124-141926514 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286371 ATP1B3-001 141876614-141926484 protein_coding
  ENST00000462082 ATP1B3-007 141876855-141926182 protein_coding
  ENST00000465172 ATP1B3-002 141876616-141926514 nonsense_mediated_decay
  ENST00000466678 ATP1B3-003 141876806-141926481 nonsense_mediated_decay
  ENST00000475483 ATP1B3-004 141876124-141916010 protein_coding
  ENST00000482635 ATP1B3-009 141903728-141922180 retained_intron
  ENST00000484727 ATP1B3-011 141921534-141925985 processed_transcript
  ENST00000486782 ATP1B3-012 141921948-141925643 retained_intron
  ENST00000487199 ATP1B3-010 141915970-141925728 nonsense_mediated_decay
  ENST00000495216 ATP1B3-008 141877529-141913706 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000286371ENST00000462082ENST00000466678ENST00000475483ENST00000482635ENST00000484727ENST00000486782ENST00000487199ENST00000495216
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000286371 7.470±0.00 8.511±0.00 2.334±0.00 7.307±2.65 4.694±1.46 5.629±0.34 4.640±4.02 21.918±0.00 2.279±0.36 18.546±16.11 N/A 21.602±2.55 16.309±6.80 15.487±1.69
ENST00000462082 16.977±0.00 39.514±0.00 8.174±0.00 21.001±10.08 23.867±0.00 13.145±3.79 10.956±9.26 60.176±0.00 5.783±0.00 31.560±29.39 4.771±0.00 25.971±10.05 48.588±9.74 53.811±0.00
ENST00000466678 N/A N/A N/A N/A N/A N/A N/A 0.365±0.00 N/A N/A 0.758±0.00 N/A N/A N/A
ENST00000475483 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.932±0.00 N/A N/A N/A
ENST00000482635 N/A 15.703±0.00 N/A N/A 13.083±0.00 N/A N/A N/A N/A N/A N/A 22.698±0.00 19.865±0.00 23.703±4.56
ENST00000484727 N/A 16.002±0.00 N/A N/A 8.206±0.00 N/A N/A N/A N/A N/A 1.307±0.00 N/A N/A N/A
ENST00000486782 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.696±0.00 N/A N/A N/A
ENST00000487199 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.404±0.00 N/A N/A N/A
ENST00000495216 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.574±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I1 CIL_0008I1_0001 VISTA 3:141560621-142161968
CIL_00052E CIL_00052E_0002 CGP 3:141778148-141926514
CIL_00052D CIL_00052D_0002 CGP 3:141876124-142000353

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001671 IDA ATPase activator activity
GO:0005391 IDA sodium:potassium-exchanging ATPase activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005890 IDA:IEA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006810 TAS transport
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0007596 TAS blood coagulation
GO:0010107 IDA potassium ion import
GO:0030001 IEA metal ion transport
GO:0030007 IDA cellular potassium ion homeostasis
GO:0032781 IDA positive regulation of ATPase activity
GO:0034220 TAS ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0036376 IDA sodium ion export from cell
GO:0050821 IDA protein stabilization
GO:0050900 TAS leukocyte migration
GO:0051117 IPI ATPase binding
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0072659 IDA protein localization to plasma membrane
GO:0086009 IDA membrane repolarization
GO:1901018 IDA positive regulation of potassium ion transmembrane transporter activity
GO:1903278 IDA positive regulation of sodium ion export from cell
GO:1903288 IDA positive regulation of potassium ion import
GO:1903291 IDA positive regulation of ATP catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015790 atp1b3a ATPase, Na+/K+ transporting, beta 3a polypeptide protein_coding Danio_rerio
ENSDARG00000042837 atp1b3b ATPase, Na+/K+ transporting, beta 3b polypeptide protein_coding Danio_rerio
ENSMUSG00000032412 Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide protein_coding Mus_musculus

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