C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanylate cyclase 2C (heat stable enterotoxin receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070019 GUCY2C 9606 - 12:14612632-14696585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261170 GUCY2C-001 14612632-14696585 protein_coding
  ENST00000535803 GUCY2C-002 14674292-14696575 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonOvaryENST00000261170
Transcript ID Brain Breast Colon Ovary
ENST00000261170 0.113±0.00 4.346±0.00 4.151±2.28 13.343±10.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HC CIL_0003HC_0001 CGP 12:14503661-14696585

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004383 IEA guanylate cyclase activity
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006182 IEA cGMP biosynthetic process
GO:0006468 IEA protein phosphorylation
GO:0007168 TAS receptor guanylyl cyclase signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0009636 IEA response to toxic substance
GO:0015643 IEA toxic substance binding
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0035556 IEA intracellular signal transduction
GO:0042127 IEA regulation of cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014320 gucy2c guanylate cyclase 2C protein_coding Danio_rerio
ENSDARG00000056045 GUCY2C (2 of 2) guanylate cyclase 2C (heat stable enterotoxin receptor) protein_coding Danio_rerio
ENSMUSG00000042638 Gucy2c guanylate cyclase 2c protein_coding Mus_musculus

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