C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanylate cyclase 2c
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042638 Gucy2c 10090 - 6:136697285-136781765 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032338 Gucy2c-001 136697285-136781765 protein_coding
  ENSMUST00000078095 Gucy2c-002 136697285-136781742 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032338ENSMUST00000078095
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032338 N/A N/A 0.182±0.10 N/A 46.846±9.31 N/A N/A 0.237±0.16 N/A N/A 0.078±0.06 0.602±0.48 0.109±0.06
ENSMUST00000078095 0.029±0.01 0.020±0.00 N/A 0.033±0.01 6.681±0.00 0.007±0.00 0.012±0.00 0.116±0.02 0.052±0.04 0.013±0.00 0.046±0.03 0.254±0.00 0.096±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00096F CIL_00096F_0002 VISTA 6:136167244-136769677
CIL_00082T CIL_00082T_0002 VISTA 6:136168119-136771874
CIL_0003HC CIL_0003HC_0002 CGP 6:136612070-136781765

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004383 IMP guanylate cyclase activity
GO:0004672 IEA protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006182 IDA cGMP biosynthetic process
GO:0006468 IEA protein phosphorylation
GO:0009636 IMP response to toxic substance
GO:0015643 IEA toxic substance binding
GO:0016021 IEA integral component of membrane
GO:0035556 IEA intracellular signal transduction
GO:0042127 IGI regulation of cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014320 gucy2c guanylate cyclase 2C protein_coding Danio_rerio
ENSDARG00000056045 GUCY2C (2 of 2) guanylate cyclase 2C (heat stable enterotoxin receptor) protein_coding Danio_rerio
ENSG00000070019 GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) protein_coding Homo_sapiens

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