C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell division cycle 42
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070831 CDC42 9606 + 1:22052627-22092946 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315554 CDC42-002 22052689-22090804 protein_coding
  ENST00000344548 CDC42-001 22052668-22092946 protein_coding
  ENST00000400259 CDC42-201 22052627-22092923 protein_coding
  ENST00000411827 CDC42-004 22053297-22086790 protein_coding
  ENST00000498236 CDC42-003 22052707-22090010 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryTestisENST00000315554ENST00000344548ENST00000400259
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Testis
ENST00000315554 N/A N/A 25.953±1.05 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000344548 17.069±0.00 14.966±0.00 13.134±3.46 18.545±0.87 24.429±0.00 8.674±0.36 4.189±0.00 25.112±0.00 5.347±0.00 38.929±26.39 N/A
ENST00000400259 N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.616±0.00 17.094±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002040 IEA sprouting angiogenesis
GO:0003161 IEA cardiac conduction system development
GO:0003334 IEA keratinocyte development
GO:0003924 TAS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006184 TAS:IEA GTP catabolic process
GO:0007015 IEA actin filament organization
GO:0007030 ISS Golgi organization
GO:0007088 IEA regulation of mitosis
GO:0007097 IEA nuclear migration
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0019901 IDA protein kinase binding
GO:0021762 IEP substantia nigra development
GO:0030036 IDA actin cytoskeleton organization
GO:0030141 IEA secretory granule
GO:0030175 IDA filopodium
GO:0030225 TAS macrophage differentiation
GO:0030496 IDA midbody
GO:0030742 IEA GTP-dependent protein binding
GO:0031069 IEA hair follicle morphogenesis
GO:0031256 IEA leading edge membrane
GO:0031274 IDA positive regulation of pseudopodium assembly
GO:0031295 TAS T cell costimulation
GO:0031333 IPI negative regulation of protein complex assembly
GO:0031424 IEA keratinization
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0031647 IEA regulation of protein stability
GO:0031996 IPI thioesterase binding
GO:0032467 IMP positive regulation of cytokinesis
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0034191 IPI apolipoprotein A-I receptor binding
GO:0034332 IEA adherens junction organization
GO:0034613 IEA cellular protein localization
GO:0035088 IEA establishment or maintenance of apical/basal cell polarity
GO:0035264 IEA multicellular organism growth
GO:0036336 IEA dendritic cell migration
GO:0036464 IDA cytoplasmic ribonucleoprotein granule
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042176 IEA regulation of protein catabolic process
GO:0042692 TAS muscle cell differentiation
GO:0042802 IPI identical protein binding
GO:0042995 IEA cell projection
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043497 IEA regulation of protein heterodimerization activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 TAS innate immune response
GO:0045177 IEA apical part of cell
GO:0045740 IEA positive regulation of DNA replication
GO:0045859 IEA regulation of protein kinase activity
GO:0046330 IEA positive regulation of JNK cascade
GO:0046847 IEA filopodium assembly
GO:0048554 IEA positive regulation of metalloenzyme activity
GO:0048664 IEA neuron fate determination
GO:0048730 IEA epidermis morphogenesis
GO:0051017 IEA actin filament bundle assembly
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051233 IDA spindle midzone
GO:0051246 IEA regulation of protein metabolic process
GO:0051489 IDA regulation of filopodium assembly
GO:0051647 IEA nucleus localization
GO:0051683 ISS establishment of Golgi localization
GO:0051835 IEA positive regulation of synapse structural plasticity
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0060047 IEA heart contraction
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060661 IEA submandibular salivary gland formation
GO:0060684 IEA epithelial-mesenchymal cell signaling
GO:0060789 IEA hair follicle placode formation
GO:0070062 IDA extracellular vesicular exosome
GO:0071338 IEA positive regulation of hair follicle cell proliferation
GO:0071944 IEA cell periphery
GO:0072384 ISS organelle transport along microtubule
GO:0072686 IDA mitotic spindle
GO:0090135 IEA actin filament branching
GO:0090136 IEA epithelial cell-cell adhesion
GO:0090316 IEA positive regulation of intracellular protein transport
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057869 cdc42l2 cell division cycle 42 like 2 protein_coding Danio_rerio
ENSMUSG00000006699 Cdc42 cell division cycle 42 protein_coding Mus_musculus

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