C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor A8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070886 EPHA8 9606 + 1:22563564-22603594 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000166244 EPHA8-001 22563564-22603594 protein_coding
  ENST00000374644 EPHA8-002 22563564-22589621 protein_coding
  ENST00000538803 EPHA8-201 22563577-22589610 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartKidneyOvaryPlacentaTestisENST00000166244ENST00000374644ENST00000538803
Transcript ID Adrenal Brain Heart Kidney Ovary Placenta Testis
ENST00000166244 N/A 0.081±0.01 N/A N/A 0.010±0.00 N/A 0.852±0.45
ENST00000374644 N/A N/A 0.029±0.03 N/A N/A N/A N/A
ENST00000538803 0.052±0.00 0.312±0.20 0.034±0.02 0.038±0.00 N/A 0.043±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005004 ISS GPI-linked ephrin receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005768 IEA endosome
GO:0005887 ISS:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006929 ISS substrate-dependent cell migration
GO:0007155 IEA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 ISS axon guidance
GO:0016322 ISS neuron remodeling
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030155 ISS regulation of cell adhesion
GO:0031175 ISS neuron projection development
GO:0033628 ISS regulation of cell adhesion mediated by integrin
GO:0043005 ISS neuron projection
GO:0043410 ISS positive regulation of MAPK cascade
GO:0043552 ISS positive regulation of phosphatidylinositol 3-kinase activity
GO:0046777 ISS protein autophosphorylation
GO:0048013 ISS:IEA ephrin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023609 epha8 eph receptor A8 protein_coding Danio_rerio
ENSMUSG00000028661 Epha8 Eph receptor A8 protein_coding Mus_musculus

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