C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: EPH receptor A8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000166244 EPHA8-001 ENSG00000070886 9606 + 1:22563564-22603594 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryTestisENST00000166244
Transcript ID Brain Ovary Testis
ENST00000166244 0.081±0.01 0.010±0.00 0.852±0.45

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005004 ISS GPI-linked ephrin receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005768 IEA endosome
GO:0005887 ISS:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006929 ISS substrate-dependent cell migration
GO:0007155 IEA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 ISS axon guidance
GO:0016322 ISS neuron remodeling
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030155 ISS regulation of cell adhesion
GO:0031175 ISS neuron projection development
GO:0033628 ISS regulation of cell adhesion mediated by integrin
GO:0043005 ISS neuron projection
GO:0043410 ISS positive regulation of MAPK cascade
GO:0043552 ISS positive regulation of phosphatidylinositol 3-kinase activity
GO:0046777 ISS protein autophosphorylation
GO:0048013 ISS:IEA ephrin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030420 Epha8-001 protein_coding Mus_musculus 0 3598
ENSDART00000111108 CABZ01071964.1-201 protein_coding Danio_rerio 1e-37 163
ENSDART00000004338 epha4l-001 protein_coding Danio_rerio 1e-18 100
ENSMUST00000144573 Ephb2-005 retained_intron Mus_musculus 5e-17 95
ENSMUST00000105846 Ephb2-003 protein_coding Mus_musculus 5e-17 95
ENSMUST00000059287 Ephb2-002 protein_coding Mus_musculus 5e-17 95
ENSMUST00000105845 Ephb2-001 protein_coding Mus_musculus 5e-17 95

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