C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072736 NFATC3 9606 + 16:68084751-68229259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329524 NFATC3-003 68085658-68229259 protein_coding
  ENST00000346183 NFATC3-002 68085658-68229259 protein_coding
  ENST00000349223 NFATC3-001 68085458-68229258 protein_coding
  ENST00000379165 NFATC3-004 68085658-68192228 retained_intron
  ENST00000535127 NFATC3-021 68088701-68226934 processed_transcript
  ENST00000539828 NFATC3-007 68085441-68192210 nonsense_mediated_decay
  ENST00000549350 NFATC3-005 68084778-68192212 retained_intron
  ENST00000553077 NFATC3-006 68084751-68192212 retained_intron
  ENST00000561714 NFATC3-010 68085366-68167015 nonsense_mediated_decay
  ENST00000562171 NFATC3-012 68085446-68158073 nonsense_mediated_decay
  ENST00000562926 NFATC3-017 68085861-68226934 protein_coding
  ENST00000563288 NFATC3-020 68086701-68226934 processed_transcript
  ENST00000563319 NFATC3-014 68084751-68226934 processed_transcript
  ENST00000563796 NFATC3-019 68086638-68226934 processed_transcript
  ENST00000565750 NFATC3-024 68123030-68138784 protein_coding
  ENST00000566301 NFATC3-015 68084778-68226934 processed_transcript
  ENST00000566893 NFATC3-009 68084839-68167015 processed_transcript
  ENST00000567152 NFATC3-018 68086638-68226471 processed_transcript
  ENST00000568466 NFATC3-011 68085389-68174514 nonsense_mediated_decay
  ENST00000569766 NFATC3-013 68084751-68226471 processed_transcript
  ENST00000570212 NFATC3-016 68085861-68226471 protein_coding
  ENST00000575270 NFATC3-023 68085344-68218090 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379165ENST00000567152ENST00000569766ENST00000570212ENST00000575270
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379165 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.013±0.00 N/A N/A
ENST00000567152 N/A N/A 4.126±0.00 8.899±0.00 4.200±0.00 5.404±0.00 2.818±0.00 7.210±0.00 10.432±0.00 14.717±0.00 6.579±0.00 5.154±0.00 N/A N/A
ENST00000569766 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.715±0.00 N/A N/A N/A
ENST00000570212 8.368±0.00 11.556±0.00 N/A N/A 10.327±0.00 7.281±0.00 3.403±0.00 6.300±0.00 N/A 6.526±0.00 N/A 8.679±3.91 8.645±4.79 39.202±0.00
ENST00000575270 N/A N/A N/A N/A 3.301±0.00 N/A 0.785±0.00 N/A 3.185±0.00 6.122±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006A CIL_00006A_0001 CGP 16:68021274-68229259
CIL_00055Z CIL_00055Z_0001 CGP 16:68084751-68238102

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001569 IEA patterning of blood vessels
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006954 TAS inflammatory response
GO:0007507 IEA heart development
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0045333 IEA cellular respiration
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051145 IEA smooth muscle cell differentiation
GO:0055001 IEA muscle cell development
GO:0071277 IEA cellular response to calcium ion
GO:0071285 IEA cellular response to lithium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076297 NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 protein_coding Danio_rerio
ENSMUSG00000031902 Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 protein_coding Mus_musculus

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