C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA dehydrogenase, very long chain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072778 ACADVL 9606 + 17:7217125-7225273 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322910 ACADVL-006 7219844-7225265 nonsense_mediated_decay
  ENST00000350303 ACADVL-002 7219863-7225264 protein_coding
  ENST00000356839 ACADVL-001 7219806-7225273 protein_coding
  ENST00000542255 ACADVL-024 7223198-7225266 protein_coding
  ENST00000543245 ACADVL-007 7217125-7225266 protein_coding
  ENST00000577191 ACADVL-005 7219908-7222464 retained_intron
  ENST00000577433 ACADVL-011 7220192-7221655 retained_intron
  ENST00000577857 ACADVL-038 7219895-7222079 processed_transcript
  ENST00000578033 ACADVL-032 7224633-7225266 retained_intron
  ENST00000578269 ACADVL-013 7219878-7220676 retained_intron
  ENST00000578319 ACADVL-030 7224217-7225266 retained_intron
  ENST00000578421 ACADVL-010 7219926-7220739 retained_intron
  ENST00000578579 ACADVL-022 7223107-7223830 retained_intron
  ENST00000578711 ACADVL-003 7223505-7225236 retained_intron
  ENST00000578809 ACADVL-029 7224217-7225266 retained_intron
  ENST00000578824 ACADVL-035 7222640-7223847 retained_intron
  ENST00000579286 ACADVL-009 7219878-7222081 retained_intron
  ENST00000579391 ACADVL-028 7224104-7224611 retained_intron
  ENST00000579425 ACADVL-021 7223032-7225247 retained_intron
  ENST00000579546 ACADVL-041 7223219-7224976 protein_coding
  ENST00000579886 ACADVL-040 7219948-7221956 protein_coding
  ENST00000579894 ACADVL-027 7223925-7224516 retained_intron
  ENST00000580263 ACADVL-012 7219895-7220780 retained_intron
  ENST00000580365 ACADVL-018 7220758-7222092 retained_intron
  ENST00000581378 ACADVL-017 7220790-7222822 nonsense_mediated_decay
  ENST00000581562 ACADVL-039 7219938-7221998 processed_transcript
  ENST00000582056 ACADVL-014 7219895-7221136 retained_intron
  ENST00000582166 ACADVL-016 7220438-7221629 retained_intron
  ENST00000582356 ACADVL-008 7219860-7220922 retained_intron
  ENST00000582379 ACADVL-019 7221946-7223237 retained_intron
  ENST00000582450 ACADVL-031 7224281-7224660 retained_intron
  ENST00000583074 ACADVL-025 7223825-7224825 processed_transcript
  ENST00000583312 ACADVL-037 7219860-7221988 protein_coding
  ENST00000583760 ACADVL-036 7221279-7222146 retained_intron
  ENST00000583848 ACADVL-033 7224489-7225266 nonsense_mediated_decay
  ENST00000583850 ACADVL-023 7223687-7225261 retained_intron
  ENST00000583858 ACADVL-020 7222760-7225213 nonsense_mediated_decay
  ENST00000584103 ACADVL-015 7219903-7221021 protein_coding
  ENST00000585203 ACADVL-034 7222848-7224813 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322910ENST00000350303ENST00000356839ENST00000542255ENST00000543245ENST00000577191ENST00000582379ENST00000583850ENST00000583858ENST00000585203
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322910 N/A N/A N/A 49.836±0.00 21.155±0.00 N/A N/A N/A 49.840±0.00 N/A N/A N/A N/A
ENST00000350303 27.880±0.00 63.922±0.00 N/A 35.751±0.00 N/A N/A N/A 3.397±0.00 N/A N/A 24.080±0.00 38.845±0.00 32.445±8.90
ENST00000356839 57.008±0.00 N/A 9.420±0.00 33.760±25.50 19.439±8.46 134.312±118.46 82.635±39.52 75.514±70.06 44.314±0.00 88.927±22.15 29.144±14.88 101.895±36.00 N/A
ENST00000542255 N/A N/A 19.252±0.00 N/A 11.873±0.00 N/A N/A N/A N/A N/A 98.545±0.00 N/A N/A
ENST00000543245 N/A N/A N/A N/A N/A 6.161±0.00 N/A N/A 5.674±0.00 N/A N/A N/A N/A
ENST00000577191 N/A N/A 8.330±0.00 6.272±0.00 13.829±0.00 12.201±0.00 N/A 7.217±0.00 4.802±0.00 N/A 39.783±29.97 N/A N/A
ENST00000582379 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 88.278±0.00 N/A N/A
ENST00000583850 79.942±0.00 153.026±0.00 N/A 119.176±0.00 75.239±0.00 264.972±0.00 277.771±0.00 323.792±0.00 156.893±0.00 124.190±0.00 78.327±15.23 N/A 65.741±10.70
ENST00000583858 N/A N/A N/A 7.048±0.00 N/A N/A N/A N/A N/A N/A 77.894±0.00 124.949±0.00 56.999±0.00
ENST00000585203 N/A N/A N/A N/A N/A N/A N/A N/A 7.518±0.00 N/A 67.513±0.00 N/A 67.663±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001659 ISS temperature homeostasis
GO:0003995 TAS:IEA acyl-CoA dehydrogenase activity
GO:0004466 TAS long-chain-acyl-CoA dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 ISS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006635 TAS fatty acid beta-oxidation
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008152 IEA metabolic process
GO:0015980 TAS energy derivation by oxidation of organic compounds
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0030855 IEP epithelial cell differentiation
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0033539 ISS fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042645 IDA mitochondrial nucleoid
GO:0044255 TAS cellular lipid metabolic process
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045717 ISS negative regulation of fatty acid biosynthetic process
GO:0046322 ISS negative regulation of fatty acid oxidation
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0090181 ISS regulation of cholesterol metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016687 acadvl acyl-Coenzyme A dehydrogenase, very long chain protein_coding Danio_rerio
ENSMUSG00000018574 Acadvl acyl-Coenzyme A dehydrogenase, very long chain protein_coding Mus_musculus

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