C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 13
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000073803 MAP3K13 9606 + 3:185282941-185489097 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265026 MAP3K13-001 185363120-185489097 protein_coding
  ENST00000420577 MAP3K13-013 185437545-185465863 protein_coding
  ENST00000424227 MAP3K13-003 185282977-185482456 protein_coding
  ENST00000428617 MAP3K13-012 185328888-185428994 protein_coding
  ENST00000433092 MAP3K13-008 185328895-185451534 nonsense_mediated_decay
  ENST00000438053 MAP3K13-002 185363242-185482601 nonsense_mediated_decay
  ENST00000438798 MAP3K13-014 185285393-185291749 protein_coding
  ENST00000439882 MAP3K13-007 185428497-185447947 nonsense_mediated_decay
  ENST00000443863 MAP3K13-006 185328895-185482811 protein_coding
  ENST00000446828 MAP3K13-004 185282953-185482749 protein_coding
  ENST00000447637 MAP3K13-010 185282961-185428920 protein_coding
  ENST00000448876 MAP3K13-005 185282941-185293079 protein_coding
  ENST00000454237 MAP3K13-011 185283026-185291917 protein_coding
  ENST00000455188 MAP3K13-009 185282961-185329263 nonsense_mediated_decay
  ENST00000477582 MAP3K13-015 185437447-185443707 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265026ENST00000424227ENST00000443863ENST00000446828ENST00000448876ENST00000477582
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265026 N/A 0.744±0.00 1.325±0.00 1.746±0.57 0.650±0.00 0.410±0.00 0.200±0.00 N/A N/A 0.684±0.04 N/A 3.037±2.17 0.305±0.00 0.795±0.22
ENST00000424227 N/A N/A 1.293±0.00 N/A 1.873±0.00 2.947±0.00 N/A N/A N/A N/A N/A 9.291±0.00 N/A N/A
ENST00000443863 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.893±0.00 N/A N/A N/A N/A
ENST00000446828 N/A N/A N/A N/A N/A N/A N/A 4.351±0.00 N/A N/A N/A N/A N/A N/A
ENST00000448876 7.612±0.00 7.365±0.00 N/A 9.472±2.50 5.974±0.00 8.571±0.00 1.730±0.97 5.868±0.00 3.861±1.08 11.589±0.00 1.098±0.00 10.639±0.30 4.198±0.27 7.154±1.72
ENST00000477582 N/A N/A 15.998±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056W CIL_00056W_0001 CGP 3:185190624-185489097
CIL_0006RB CIL_0006RB_0001 CGP 3:185282941-185499057

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IDA:IEA activation of MAPKK activity
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004709 IDA:IEA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006468 IDA:IEA protein phosphorylation
GO:0007254 IDA JNK cascade
GO:0008385 IDA IkappaB kinase complex
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 ISS protein kinase binding
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0046777 IDA:IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009493 MAP3K13 mitogen-activated protein kinase kinase kinase 13 protein_coding Danio_rerio
ENSMUSG00000033618 Map3k13 mitogen-activated protein kinase kinase kinase 13 protein_coding Mus_musculus

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