C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000075388 FGF4 9606 - 11:69771016-69775403 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000168712 FGF4-001 69771016-69775403 protein_coding
  ENST00000538040 FGF4-002 69773349-69775164 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyMuscleTestisENST00000168712
Transcript ID Colon Kidney Muscle Testis
ENST00000168712 0.029±0.00 0.068±0.03 0.021±0.00 0.334±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TF CIL_0007TF_0001 VISTA 11:69193417-69797766
CIL_0003JR CIL_0003JR_0002 CGP 11:69771016-69819024

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 IEA cartilage condensation
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005634 IEA nucleus
GO:0005829 IEA cytosol
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0010463 IDA mesenchymal cell proliferation
GO:0010468 IEA regulation of gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0019827 IEA stem cell maintenance
GO:0030326 IEA embryonic limb morphogenesis
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043066 IEA negative regulation of apoptotic process
GO:0045087 TAS innate immune response
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0051781 IEA positive regulation of cell division
GO:0060363 IEA cranial suture morphogenesis
GO:0060561 IEA apoptotic process involved in morphogenesis
GO:0060591 IDA chondroblast differentiation
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068095 fgf4 fibroblast growth factor 4 protein_coding Danio_rerio
ENSMUSG00000050917 Fgf4 fibroblast growth factor 4 protein_coding Mus_musculus

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