C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB7A, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000075785 RAB7A 9606 + 3:128726122-128814796 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265062 RAB7A-001 128726122-128814796 protein_coding
  ENST00000464496 RAB7A-006 128795243-128807594 protein_coding
  ENST00000482525 RAB7A-004 128726193-128814353 protein_coding
  ENST00000483906 RAB7A-011 128795359-128813541 protein_coding
  ENST00000485280 RAB7A-012 128795359-128813644 protein_coding
  ENST00000490093 RAB7A-009 128795359-128807616 protein_coding
  ENST00000491681 RAB7A-007 128726352-128798425 retained_intron
  ENST00000493186 RAB7A-010 128795359-128813445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265062ENST00000482525ENST00000490093
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265062 101.632±0.00 72.564±0.00 11.427±0.00 53.764±49.87 52.377±35.69 40.979±30.46 42.468±36.15 50.808±43.21 30.645±18.99 55.074±42.44 81.234±0.00 62.931±32.93 102.152±28.18 56.222±27.39
ENST00000482525 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.156±25.74 63.223±0.00 18.278±0.00
ENST00000490093 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.501±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IDA:IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005525 IDA:IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IDA lysosome
GO:0005765 TAS lysosomal membrane
GO:0005770 IDA late endosome
GO:0005794 IEA Golgi apparatus
GO:0006184 IDA:IEA GTP catabolic process
GO:0006622 IMP protein targeting to lysosome
GO:0006886 IEA intracellular protein transport
GO:0006897 TAS endocytosis
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007174 IMP epidermal growth factor catabolic process
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008219 IEA cell death
GO:0008333 IMP endosome to lysosome transport
GO:0015031 IEA:TAS protein transport
GO:0016020 IEA membrane
GO:0019003 IDA GDP binding
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0031410 IEA cytoplasmic vesicle
GO:0034045 IEA pre-autophagosomal structure membrane
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045022 IMP early endosome to late endosome transport
GO:0045335 IDA phagocytic vesicle
GO:0045453 IEA bone resorption
GO:0048365 IEA Rac GTPase binding
GO:0070062 IDA extracellular vesicular exosome
GO:0090382 TAS phagosome maturation
GO:0090383 IMP phagosome acidification
GO:0090385 IMP phagosome-lysosome fusion
GO:0097208 IEA alveolar lamellar body
GO:2000785 IMP regulation of autophagic vacuole assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020497 rab7 RAB7, member RAS oncogene family protein_coding Danio_rerio
ENSDARG00000021287 RAB7A (2 of 3) RAB7A, member RAS oncogene family protein_coding Danio_rerio
ENSDARG00000087243 RAB7A (3 of 3) RAB7A, member RAS oncogene family protein_coding Danio_rerio
ENSMUSG00000079477 Rab7 RAB7, member RAS oncogene family protein_coding Mus_musculus

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