C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein inhibitor of activated STAT, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078043 PIAS2 9606 - 18:46808390-46920160 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324794 PIAS2-002 46815711-46917503 protein_coding
  ENST00000398654 PIAS2-007 46812280-46917454 nonsense_mediated_decay
  ENST00000545673 PIAS2-006 46818191-46917505 protein_coding
  ENST00000585916 PIAS2-008 46808390-46917345 protein_coding
  ENST00000586170 PIAS2-015 46891032-46917420 processed_transcript
  ENST00000586634 PIAS2-013 46905760-46917350 retained_intron
  ENST00000586953 PIAS2-014 46890809-46917079 protein_coding
  ENST00000587810 PIAS2-017 46890894-46920148 protein_coding
  ENST00000589819 PIAS2-011 46846464-46864232 retained_intron
  ENST00000589917 PIAS2-009 46890686-46920143 protein_coding
  ENST00000590127 PIAS2-003 46827758-46917474 retained_intron
  ENST00000590944 PIAS2-016 46907498-46907999 processed_transcript
  ENST00000591865 PIAS2-010 46843851-46844971 retained_intron
  ENST00000592011 PIAS2-001 46836243-46920160 retained_intron
  ENST00000592212 PIAS2-005 46826764-46906230 protein_coding
  ENST00000592221 PIAS2-012 46890894-46918041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324794ENST00000398654ENST00000545673ENST00000585916ENST00000590127ENST00000590944ENST00000592212
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324794 N/A N/A 0.892±0.00 N/A 1.037±0.00 0.494±0.00 N/A 0.593±0.00 0.847±0.51 0.600±0.00 N/A N/A 0.192±0.00 N/A
ENST00000398654 1.673±0.00 2.869±0.00 N/A 2.964±0.29 N/A N/A 2.438±0.79 3.360±1.42 2.786±1.06 1.760±0.00 2.817±0.00 1.379±0.00 3.523±0.00 14.120±0.00
ENST00000545673 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.316±0.00
ENST00000585916 1.085±0.00 N/A N/A 1.795±0.59 1.586±0.38 0.912±0.13 1.986±0.00 2.969±0.00 0.759±0.00 1.009±0.10 2.733±0.00 1.382±0.54 0.355±0.19 3.623±0.00
ENST00000590127 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.854±0.00 N/A 1.513±0.00 68.822±50.97
ENST00000590944 N/A N/A N/A N/A N/A N/A 0.027±0.00 N/A N/A 0.113±0.00 N/A N/A N/A 0.126±0.00
ENST00000592212 N/A N/A N/A 2.464±0.00 N/A 1.446±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003713 NAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0008152 IEA metabolic process
GO:0008270 IEA zinc ion binding
GO:0016604 IEA nuclear body
GO:0016605 IDA PML body
GO:0016925 IEA protein sumoylation
GO:0019789 IEA:IDA SUMO ligase activity
GO:0030521 NAS androgen receptor signaling pathway
GO:0031625 IEA ubiquitin protein ligase binding
GO:0045667 IEA regulation of osteoblast differentiation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050681 NAS androgen receptor binding
GO:0060766 IDA negative regulation of androgen receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092979 pias2 protein inhibitor of activated STAT, 2 protein_coding Danio_rerio
ENSMUSG00000025423 Pias2 protein inhibitor of activated STAT 2 protein_coding Mus_musculus

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