C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein inhibitor of activated STAT 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025423 Pias2 10090 + 18:77065208-77155708 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114776 Pias2-201 77065680-77146939 protein_coding
  ENSMUST00000114777 Pias2-202 77065208-77155708 protein_coding
  ENSMUST00000168882 Pias2-203 77065680-77155708 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114776ENSMUST00000114777ENSMUST00000168882
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114776 N/A 3.891±0.00 N/A N/A N/A N/A N/A N/A 1.890±0.00 2.169±0.00 N/A 4.656±1.89 3.913±1.98 96.601±27.93
ENSMUST00000114777 4.395±1.88 8.565±2.27 7.652±0.09 12.945±6.73 7.987±3.87 5.184±0.61 3.425±0.95 11.247±3.77 5.712±0.75 6.775±1.99 7.882±0.90 9.160±3.40 4.482±2.48 16.240±7.30
ENSMUST00000168882 4.136±0.85 4.423±0.32 N/A N/A 4.402±1.21 2.206±0.75 1.179±0.64 3.799±0.58 1.230±0.32 3.368±1.30 N/A 3.428±1.64 0.854±0.06 16.347±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DZ CIL_0008DZ_0002 VISTA 18:76562703-77163723

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IDA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0016604 IDA nuclear body
GO:0016605 ISS PML body
GO:0016925 IDA protein sumoylation
GO:0019789 IDA SUMO ligase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045667 IMP regulation of osteoblast differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050681 ISO androgen receptor binding
GO:0060765 ISO regulation of androgen receptor signaling pathway
GO:0060766 IEA negative regulation of androgen receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092979 pias2 protein inhibitor of activated STAT, 2 protein_coding Danio_rerio
ENSG00000078043 PIAS2 protein inhibitor of activated STAT, 2 protein_coding Homo_sapiens

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