C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAP kinase interacting serine/threonine kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079277 MKNK1 9606 - 1:46557408-46616843 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341183 MKNK1-201 46557408-46604294 protein_coding
  ENST00000342571 MKNK1-002 46557418-46585971 nonsense_mediated_decay
  ENST00000371945 MKNK1-004 46557419-46604237 protein_coding
  ENST00000371946 MKNK1-001 46557418-46604214 protein_coding
  ENST00000428112 MKNK1-016 46558699-46604255 protein_coding
  ENST00000460098 MKNK1-007 46562749-46568462 processed_transcript
  ENST00000465783 MKNK1-010 46580434-46594280 protein_coding
  ENST00000468852 MKNK1-013 46593523-46604270 retained_intron
  ENST00000470237 MKNK1-006 46561572-46568437 processed_transcript
  ENST00000474868 MKNK1-011 46580440-46594261 nonsense_mediated_decay
  ENST00000477883 MKNK1-012 46584504-46586269 retained_intron
  ENST00000480531 MKNK1-009 46576268-46585935 retained_intron
  ENST00000484301 MKNK1-005 46573734-46594206 retained_intron
  ENST00000486716 MKNK1-008 46574826-46594231 retained_intron
  ENST00000496619 MKNK1-014 46568456-46604294 protein_coding
  ENST00000524417 MKNK1-024 46562699-46565426 retained_intron
  ENST00000524749 MKNK1-026 46558233-46565063 protein_coding
  ENST00000525888 MKNK1-021 46584547-46604246 processed_transcript
  ENST00000526513 MKNK1-028 46572158-46604224 nonsense_mediated_decay
  ENST00000528077 MKNK1-015 46558393-46604268 nonsense_mediated_decay
  ENST00000528237 MKNK1-022 46572109-46586259 protein_coding
  ENST00000529170 MKNK1-018 46576584-46604255 protein_coding
  ENST00000530528 MKNK1-025 46561477-46563035 retained_intron
  ENST00000531355 MKNK1-017 46561482-46604279 nonsense_mediated_decay
  ENST00000531769 MKNK1-020 46576589-46616843 protein_coding
  ENST00000532110 MKNK1-019 46580596-46595059 protein_coding
  ENST00000532783 MKNK1-027 46568443-46585560 protein_coding
  ENST00000532897 MKNK1-023 46558756-46572300 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341183ENST00000342571ENST00000371945ENST00000371946ENST00000468852ENST00000484301ENST00000528077
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341183 N/A N/A 1.602±0.00 N/A 1.710±0.00 N/A N/A N/A N/A N/A N/A N/A 3.784±0.00 2.904±0.00
ENST00000342571 N/A N/A N/A 2.250±0.00 4.823±0.00 2.809±0.00 3.449±0.00 N/A 2.073±0.00 N/A N/A 5.224±0.00 N/A N/A
ENST00000371945 5.736±0.00 5.094±0.00 N/A 1.511±0.00 1.784±0.00 2.652±0.00 2.343±0.00 N/A N/A 3.715±0.00 N/A 6.851±1.55 9.403±2.45 4.075±0.00
ENST00000371946 N/A 5.252±0.00 N/A 4.045±0.00 3.402±0.00 2.563±0.00 1.654±0.00 6.746±0.00 2.307±0.00 8.475±0.00 4.126±0.00 N/A N/A 3.190±0.00
ENST00000468852 N/A N/A 18.334±0.00 6.204±0.00 N/A 20.117±0.00 N/A 10.408±0.00 N/A 13.011±0.00 N/A N/A N/A N/A
ENST00000484301 N/A N/A N/A 1.114±0.00 1.306±0.00 2.525±0.00 N/A 0.598±0.00 N/A 1.600±0.00 N/A N/A N/A N/A
ENST00000528077 N/A N/A N/A N/A N/A N/A 1.007±0.00 N/A N/A N/A 1.764±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006417 IEA regulation of translation
GO:0006446 IEA regulation of translational initiation
GO:0006468 IEA protein phosphorylation
GO:0008152 IEA metabolic process
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0009651 IEA response to salt stress
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0035556 IDA intracellular signal transduction
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018411 mknk1 MAP kinase interacting serine/threonine kinase 1 protein_coding Danio_rerio
ENSMUSG00000028708 Mknk1 MAP kinase-interacting serine/threonine kinase 1 protein_coding Mus_musculus

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