C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAP kinase-interacting serine/threonine kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028708 Mknk1 10090 + 4:115839198-115879250 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019677 Mknk1-001 115839198-115879250 protein_coding
  ENSMUST00000106513 Mknk1-201 115839233-115879250 protein_coding
  ENSMUST00000130819 Mknk1-006 115839235-115866532 protein_coding
  ENSMUST00000135209 Mknk1-013 115874771-115877052 processed_transcript
  ENSMUST00000140315 Mknk1-007 115839244-115857097 protein_coding
  ENSMUST00000140585 Mknk1-009 115839260-115863261 processed_transcript
  ENSMUST00000144235 Mknk1-003 115839198-115879250 processed_transcript
  ENSMUST00000144427 Mknk1-004 115839221-115864565 protein_coding
  ENSMUST00000150201 Mknk1-008 115857106-115876610 processed_transcript
  ENSMUST00000151203 Mknk1-005 115839240-115864602 protein_coding
  ENSMUST00000152888 Mknk1-012 115857032-115878664 processed_transcript
  ENSMUST00000153766 Mknk1-002 115839223-115873870 processed_transcript
  ENSMUST00000154957 Mknk1-011 115866267-115867327 processed_transcript
  ENSMUST00000155412 Mknk1-010 115839233-115848579 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019677ENSMUST00000106513ENSMUST00000135209ENSMUST00000144235ENSMUST00000150201ENSMUST00000152888
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019677 10.033±1.59 14.209±5.90 15.781±2.73 8.662±2.44 8.306±3.12 5.451±0.99 2.472±0.66 8.301±1.15 16.332±10.81 14.609±6.95 2.782±0.78 10.003±2.86 7.457±3.47 5.603±1.71
ENSMUST00000106513 3.407±0.00 N/A N/A N/A 5.003±1.81 N/A N/A N/A 2.543±0.49 N/A 1.530±0.00 N/A N/A N/A
ENSMUST00000135209 N/A 11.016±0.00 N/A N/A 11.125±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000144235 N/A 3.199±0.00 N/A N/A N/A 2.616±0.00 2.721±0.37 N/A N/A N/A 2.798±0.00 N/A N/A 1.495±0.49
ENSMUST00000150201 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.267±0.00 7.076±0.00
ENSMUST00000152888 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.010±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SB CIL_0001SB_0002 CGP 4:115828092-115879250

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA:IDA ATP binding
GO:0006417 IEA regulation of translation
GO:0006446 IEA regulation of translational initiation
GO:0006468 IDA protein phosphorylation
GO:0009651 IDA response to salt stress
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0035556 IDA intracellular signal transduction
GO:0097192 IGI extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018411 mknk1 MAP kinase interacting serine/threonine kinase 1 protein_coding Danio_rerio
ENSG00000079277 MKNK1 MAP kinase interacting serine/threonine kinase 1 protein_coding Homo_sapiens

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