C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dynamin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000079805 DNM2 9606 + 19:10718079-10833488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355667 DNM2-001 10718163-10831895 protein_coding
  ENST00000359692 DNM2-002 10718093-10831884 protein_coding
  ENST00000389253 DNM2-010 10718131-10831903 protein_coding
  ENST00000408974 DNM2-003 10718208-10831424 protein_coding
  ENST00000585892 DNM2-006 10718079-10831047 protein_coding
  ENST00000586130 DNM2-011 10786430-10786741 retained_intron
  ENST00000586939 DNM2-012 10718561-10777154 protein_coding
  ENST00000587329 DNM2-021 10798387-10802599 retained_intron
  ENST00000587485 DNM2-018 10781374-10793751 processed_transcript
  ENST00000587830 DNM2-022 10783016-10812300 protein_coding
  ENST00000587991 DNM2-015 10768553-10775815 processed_transcript
  ENST00000588976 DNM2-013 10755121-10759801 processed_transcript
  ENST00000589106 DNM2-023 10829112-10830534 protein_coding
  ENST00000590787 DNM2-009 10809208-10824806 retained_intron
  ENST00000590806 DNM2-008 10808519-10831897 retained_intron
  ENST00000591118 DNM2-017 10781374-10783113 processed_transcript
  ENST00000591266 DNM2-014 10763099-10772507 processed_transcript
  ENST00000591701 DNM2-019 10777169-10795746 retained_intron
  ENST00000591818 DNM2-024 10830338-10833488 protein_coding
  ENST00000591819 DNM2-016 10769289-10777202 processed_transcript
  ENST00000593203 DNM2-007 10823224-10833484 retained_intron
  ENST00000593220 DNM2-020 10795716-10798562 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355667ENST00000359692ENST00000389253ENST00000408974ENST00000585892ENST00000587830ENST00000591701
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355667 11.667±0.00 11.792±0.00 N/A N/A 8.750±0.00 19.473±0.00 N/A 12.802±10.49 11.246±0.00 20.026±0.00 N/A 22.247±10.35 24.178±3.66 16.735±1.36
ENST00000359692 11.248±0.00 16.413±0.00 N/A 4.326±3.62 14.080±0.00 8.534±0.00 8.837±7.42 27.998±0.00 6.287±0.00 16.594±0.00 42.463±0.00 9.622±4.41 17.109±0.68 12.816±0.00
ENST00000389253 21.725±0.00 28.931±0.00 N/A 14.500±13.66 9.191±0.00 5.275±0.00 25.147±0.00 29.404±0.00 3.001±0.00 27.544±0.00 N/A 12.276±0.22 16.791±1.69 16.734±3.94
ENST00000408974 N/A N/A N/A 12.401±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000585892 N/A N/A 5.574±0.00 1.868±0.00 9.846±0.00 N/A 1.477±0.00 4.118±0.00 6.450±0.00 12.209±0.00 3.058±0.00 7.350±0.00 11.692±0.00 9.362±0.00
ENST00000587830 N/A N/A 7.935±0.00 4.224±0.00 N/A N/A N/A N/A N/A N/A 6.632±0.00 N/A 37.998±0.00 39.561±0.00
ENST00000591701 N/A N/A 12.349±0.00 N/A 12.623±0.00 30.925±0.00 N/A N/A N/A 20.287±0.00 N/A 10.417±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076W CIL_00076W_0002 CGP 19:10701430-10833488
CIL_000770 CIL_000770_0002 CGP 19:10718079-10836318

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 NAS G2/M transition of mitotic cell cycle
GO:0000139 TAS Golgi membrane
GO:0003924 IEA:NAS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA:NAS GTP binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005874 IDA microtubule
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0006897 NAS endocytosis
GO:0007165 NAS signal transduction
GO:0008017 NAS microtubule binding
GO:0008219 IEA cell death
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019899 NAS enzyme binding
GO:0030666 TAS endocytic vesicle membrane
GO:0031623 IMP receptor internalization
GO:0033572 IMP transferrin transport
GO:0043065 NAS positive regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0045211 IDA postsynaptic membrane
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0046209 TAS nitric oxide metabolic process
GO:0048489 NAS synaptic vesicle transport
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020270 DNM2 (1 of 2) dynamin 2 protein_coding Danio_rerio
ENSDARG00000069937 dnm2a dynamin 2a protein_coding Danio_rerio
ENSMUSG00000033335 Dnm2 dynamin 2 protein_coding Mus_musculus

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