C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, L type, alpha 1S subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000081248 CACNA1S 9606 - 1:201039512-201112566 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000362061 CACNA1S-001 201039514-201112566 protein_coding
  ENST00000367338 CACNA1S-002 201039512-201112451 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000362061ENST00000367338
Transcript ID Adipose Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000362061 N/A 0.163±0.09 4.431±0.00 N/A N/A N/A N/A 42.320±6.60 0.001±0.00 N/A N/A
ENST00000367338 0.010±0.00 N/A 0.039±0.00 0.007±0.00 0.110±0.00 0.128±0.00 0.049±0.04 20.337±0.00 0.021±0.01 0.038±0.02 0.742±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0002074 IEA extraocular skeletal muscle development
GO:0005216 IEA ion channel activity
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006811 IEA ion transport
GO:0006816 IDA calcium ion transport
GO:0006936 IMP muscle contraction
GO:0006941 IEA striated muscle contraction
GO:0007029 IEA endoplasmic reticulum organization
GO:0007411 TAS axon guidance
GO:0007519 IEA skeletal muscle tissue development
GO:0007520 IEA myoblast fusion
GO:0007528 IEA neuromuscular junction development
GO:0008331 IDA high voltage-gated calcium channel activity
GO:0016020 IEA membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0030315 IDA T-tubule
GO:0031674 IDA I band
GO:0034765 IEA regulation of ion transmembrane transport
GO:0043501 IEA skeletal muscle adaptation
GO:0046872 IEA metal ion binding
GO:0048741 IEA skeletal muscle fiber development
GO:0055001 IEA muscle cell development
GO:0055085 IEA transmembrane transport
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029457 cacna1sa calcium channel, voltage-dependent, L type, alpha 1S subunit, a protein_coding Danio_rerio
ENSDARG00000042552 cacna1sb calcium channel, voltage-dependent, L type, alpha 1S subunit, b protein_coding Danio_rerio
ENSMUSG00000026407 Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit protein_coding Mus_musculus

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