C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, L type, alpha 1S subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026407 Cacna1s 10090 + 1:136052750-136119822 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000112064 Cacna1s-201 136052901-136119822 protein_coding
  ENSMUST00000112068 Cacna1s-001 136052784-136119535 protein_coding
  ENSMUST00000159106 Cacna1s-005 136117256-136119529 processed_transcript
  ENSMUST00000160641 Cacna1s-002 136052750-136119530 protein_coding
  ENSMUST00000161700 Cacna1s-004 136105406-136112058 retained_intron
  ENSMUST00000161865 Cacna1s-003 136073554-136119529 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112064ENSMUST00000112068ENSMUST00000159106ENSMUST00000160641ENSMUST00000161700ENSMUST00000161865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112064 N/A N/A 0.001±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.141±0.00 N/A N/A
ENSMUST00000112068 N/A N/A N/A 0.009±0.00 N/A N/A N/A 0.029±0.00 0.025±0.02 N/A N/A N/A 0.043±0.02 N/A
ENSMUST00000159106 0.086±0.05 0.105±0.00 0.073±0.04 N/A 0.580±0.31 0.766±0.20 2.108±0.00 0.073±0.00 0.041±0.02 1.607±0.20 N/A 0.850±0.15 0.123±0.06 2.656±0.65
ENSMUST00000160641 N/A N/A N/A 0.023±0.01 24.997±6.52 N/A N/A 1.142±0.05 N/A 1.477±0.09 145.360±11.08 0.165±0.00 N/A N/A
ENSMUST00000161700 0.025±0.00 0.145±0.08 N/A N/A N/A N/A N/A N/A 0.015±0.01 N/A N/A 1.177±0.60 0.120±0.03 3.228±0.65
ENSMUST00000161865 0.008±0.00 0.013±0.00 0.006±0.00 0.019±0.01 11.780±0.00 N/A N/A 0.047±0.01 0.011±0.01 N/A N/A 0.283±0.15 0.047±0.05 0.332±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0002074 IMP extraocular skeletal muscle development
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005891 IEA voltage-gated calcium channel complex
GO:0006816 IMP calcium ion transport
GO:0006936 IMP muscle contraction
GO:0006941 IMP striated muscle contraction
GO:0007029 IMP endoplasmic reticulum organization
GO:0007519 IMP skeletal muscle tissue development
GO:0007520 IMP myoblast fusion
GO:0007528 IMP neuromuscular junction development
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0016529 IDA sarcoplasmic reticulum
GO:0030315 IDA T-tubule
GO:0031674 IEA I band
GO:0034765 IEA regulation of ion transmembrane transport
GO:0043501 IMP skeletal muscle adaptation
GO:0048741 IMP skeletal muscle fiber development
GO:0055001 IMP muscle cell development
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029457 cacna1sa calcium channel, voltage-dependent, L type, alpha 1S subunit, a protein_coding Danio_rerio
ENSDARG00000042552 cacna1sb calcium channel, voltage-dependent, L type, alpha 1S subunit, b protein_coding Danio_rerio
ENSG00000081248 CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit protein_coding Homo_sapiens

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