C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 12 receptor, beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000081985 IL12RB2 9606 + 1:67307364-67396900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262345 IL12RB2-001 67307364-67396900 protein_coding
  ENST00000371000 IL12RB2-201 67307364-67396900 protein_coding
  ENST00000441640 IL12RB2-002 67326769-67338750 protein_coding
  ENST00000465396 IL12RB2-003 67379928-67395763 processed_transcript
  ENST00000541374 IL12RB2-202 67307364-67396900 protein_coding
  ENST00000544434 IL12RB2-203 67307364-67396900 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262345ENST00000371000ENST00000441640ENST00000465396ENST00000541374ENST00000544434
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262345 N/A 0.291±0.00 0.106±0.00 0.505±0.30 0.072±0.00 0.021±0.00 0.149±0.00 0.131±0.00 N/A N/A 3.668±0.00 0.063±0.02 N/A 0.191±0.00
ENST00000371000 0.178±0.00 N/A N/A N/A N/A N/A 0.072±0.00 0.060±0.00 N/A N/A N/A N/A 0.650±0.00 0.039±0.00
ENST00000441640 0.191±0.00 N/A N/A 2.264±0.00 N/A 0.666±0.00 N/A 0.476±0.00 2.353±0.00 0.441±0.00 1.941±0.00 0.742±0.61 3.266±0.00 0.515±0.00
ENST00000465396 N/A N/A N/A N/A N/A 0.480±0.00 N/A N/A 0.087±0.00 N/A N/A 0.154±0.00 N/A N/A
ENST00000541374 N/A N/A N/A N/A 0.171±0.00 N/A N/A N/A N/A N/A N/A 0.176±0.00 0.893±0.00 0.053±0.00
ENST00000544434 N/A N/A N/A N/A N/A 0.044±0.00 N/A N/A 0.004±0.00 0.231±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004896 TAS cytokine receptor activity
GO:0005515 IEA protein binding
GO:0005887 TAS integral component of plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008284 TAS positive regulation of cell proliferation
GO:0009897 IEA external side of plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019901 IEA protein kinase binding
GO:0032496 IEA response to lipopolysaccharide
GO:0032609 IEA interferon-gamma production
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0034097 IEA response to cytokine

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052157 il12rb2 interleukin 12 receptor, beta 2a protein_coding Danio_rerio
ENSDARG00000093809 IL12RB2 (2 of 2) interleukin 12 receptor, beta 2 protein_coding Danio_rerio
ENSMUSG00000018341 Il12rb2 interleukin 12 receptor, beta 2 protein_coding Mus_musculus

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