C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 12 receptor, beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018341 Il12rb2 10090 - 6:67291318-67376188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018485 Il12rb2-001 67292018-67376188 protein_coding
  ENSMUST00000117441 Il12rb2-002 67291318-67339694 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018485ENSMUST00000117441
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018485 0.112±0.07 0.114±0.01 N/A 0.339±0.16 0.095±0.00 0.069±0.02 0.148±0.05 0.461±0.15 N/A 0.234±0.01 0.031±0.00 N/A
ENSMUST00000117441 0.095±0.02 0.081±0.03 1.195±0.37 0.145±0.00 0.096±0.06 N/A 0.401±0.25 N/A 1.575±0.14 0.198±0.09 0.064±0.04 0.066±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004QS CIL_0004QS_0003 CGP 6:67266979-67376188

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004896 IEA cytokine receptor activity
GO:0005515 IPI protein binding
GO:0009897 IDA external side of plasma membrane
GO:0016021 IEA integral component of membrane
GO:0018108 IMP peptidyl-tyrosine phosphorylation
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019901 IPI protein kinase binding
GO:0032496 IGI response to lipopolysaccharide
GO:0032609 IGI interferon-gamma production
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0034097 IMP response to cytokine

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052157 il12rb2 interleukin 12 receptor, beta 2a protein_coding Danio_rerio
ENSDARG00000093809 IL12RB2 (2 of 2) interleukin 12 receptor, beta 2 protein_coding Danio_rerio
ENSG00000081985 IL12RB2 interleukin 12 receptor, beta 2 protein_coding Homo_sapiens

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