C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: unc-51 like autophagy activating kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000083290 ULK2 9606 - 17:19770829-19867936 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361658 ULK2-002 19770830-19867936 protein_coding
  ENST00000395544 ULK2-001 19773950-19867917 protein_coding
  ENST00000570983 ULK2-004 19770829-19773924 retained_intron
  ENST00000571137 ULK2-008 19781961-19796289 retained_intron
  ENST00000571177 ULK2-006 19816466-19843138 processed_transcript
  ENST00000571454 ULK2-010 19781086-19784060 retained_intron
  ENST00000574732 ULK2-005 19838530-19849379 nonsense_mediated_decay
  ENST00000574854 ULK2-007 19804727-19811237 processed_transcript
  ENST00000575432 ULK2-009 19781889-19796127 protein_coding
  ENST00000580118 ULK2-012 19841540-19864836 nonsense_mediated_decay
  ENST00000580130 ULK2-014 19797575-19838504 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361658ENST00000395544ENST00000571137
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361658 2.922±0.00 0.624±0.00 1.485±0.00 3.303±0.45 2.215±1.02 1.004±0.54 1.618±0.96 0.721±0.40 1.077±0.75 1.238±0.57 0.728±0.00 1.869±0.00 0.786±0.16 7.469±2.45
ENST00000395544 3.075±0.00 1.234±0.00 N/A 5.742±1.71 1.492±0.65 1.942±1.19 1.479±0.76 1.334±0.00 0.752±0.47 1.596±0.04 0.923±0.12 2.230±1.56 1.709±0.36 11.184±2.16
ENST00000571137 N/A N/A N/A N/A N/A N/A N/A 0.831±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077F CIL_00077F_0002 CGP 17:19737984-19867936
CIL_00013V CIL_00013V_0001 CGP 17:19770829-19978343

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IBA autophagic vacuole assembly
GO:0003824 IEA catalytic activity
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 IBA cytosol
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0007409 IEA axonogenesis
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0010506 IDA regulation of autophagy
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0031410 IEA cytoplasmic vesicle
GO:0034045 IDA pre-autophagosomal structure membrane
GO:0034273 IBA ATG1/UKL1 signaling complex
GO:0042594 ISS response to starvation
GO:0046777 IDA protein autophosphorylation
GO:0048671 IEA negative regulation of collateral sprouting
GO:0048675 IBA axon extension

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000097205 ulk2 unc-51-like kinase 2 (C. elegans) protein_coding Danio_rerio
ENSMUSG00000004798 Ulk2 unc-51 like kinase 2 protein_coding Mus_musculus

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