C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: unc-51 like kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004798 Ulk2 10090 - 11:61775649-61855073 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004920 Ulk2-001 61775649-61855073 protein_coding
  ENSMUST00000129025 Ulk2-002 61777502-61854502 processed_transcript
  ENSMUST00000157049 Ulk2-003 61799902-61804021 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004920ENSMUST00000129025ENSMUST00000157049
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004920 9.980±1.65 17.954±3.62 6.488±0.44 13.042±8.27 12.722±3.63 4.290±1.20 8.082±0.59 5.570±1.86 3.942±2.52 14.264±2.95 20.290±2.54 8.345±4.05 3.857±2.51 20.808±6.71
ENSMUST00000129025 12.907±2.73 N/A 3.214±1.07 11.670±2.44 11.724±1.99 3.324±0.00 11.029±1.11 6.730±1.55 4.452±3.43 8.982±3.16 N/A 7.851±2.64 5.411±2.32 39.060±8.42
ENSMUST00000157049 N/A N/A N/A N/A 22.955±0.78 12.331±0.88 N/A 8.839±0.90 11.149±1.24 17.241±0.00 N/A 21.474±3.66 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013V CIL_00013V_0002 CGP 11:61775649-61930252

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IBA autophagic vacuole assembly
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 IBA cytosol
GO:0007165 IEA signal transduction
GO:0010506 IMP regulation of autophagy
GO:0031410 IEA cytoplasmic vesicle
GO:0034045 IDA pre-autophagosomal structure membrane
GO:0034273 IBA ATG1/UKL1 signaling complex
GO:0042594 IDA response to starvation
GO:0046777 IBA protein autophosphorylation
GO:0048671 IMP negative regulation of collateral sprouting
GO:0048675 IMP axon extension

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000097205 ulk2 unc-51-like kinase 2 (C. elegans) protein_coding Danio_rerio
ENSG00000083290 ULK2 unc-51 like autophagy activating kinase 2 protein_coding Homo_sapiens

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