C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000085741 WNT11 9606 - 11:76186325-76210736 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322563 WNT11-001 76186325-76206532 protein_coding
  ENST00000529461 WNT11-004 76206392-76210736 protein_coding
  ENST00000532150 WNT11-003 76206422-76210730 processed_transcript
  ENST00000621122 WNT11-201 76187065-76206407 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322563ENST00000529461ENST00000532150ENST00000621122
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322563 4.832±0.00 1.565±0.00 N/A 2.712±2.04 1.665±1.38 N/A 0.137±0.00 N/A 0.612±0.00 0.702±0.06 1.518±0.21 3.169±0.54 1.035±0.87
ENST00000529461 N/A N/A N/A N/A N/A 0.414±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000532150 N/A N/A 1.434±0.00 N/A N/A N/A 2.179±0.00 N/A N/A 4.160±0.00 N/A N/A N/A
ENST00000621122 N/A 0.983±0.00 0.177±0.00 7.726±0.00 4.900±0.00 0.705±0.00 0.464±0.00 1.009±0.00 4.834±0.00 N/A 0.953±0.00 4.268±2.00 0.917±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000927 CIL_000927_0001 VISTA 11:75746993-76349575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0001822 IEA kidney development
GO:0003151 IEA outflow tract morphogenesis
GO:0005099 IMP Ras GTPase activator activity
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005515 IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 IDA cytoplasm
GO:0006468 IMP protein phosphorylation
GO:0007275 IEA multicellular organismal development
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0030154 IEA cell differentiation
GO:0030182 ISS neuron differentiation
GO:0030282 IEA bone mineralization
GO:0030295 IMP protein kinase activator activity
GO:0030308 IMP negative regulation of cell growth
GO:0030325 IEP adrenal gland development
GO:0030335 IMP positive regulation of cell migration
GO:0030336 IMP negative regulation of cell migration
GO:0031012 IEA extracellular matrix
GO:0031667 IEA response to nutrient levels
GO:0032320 IMP positive regulation of Ras GTPase activity
GO:0032915 IEA positive regulation of transforming growth factor beta2 production
GO:0034394 IMP protein localization to cell surface
GO:0035567 IEA non-canonical Wnt signaling pathway
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045165 IBA cell fate commitment
GO:0045860 IMP positive regulation of protein kinase activity
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048706 IEP embryonic skeletal system development
GO:0048844 IEA artery morphogenesis
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0060021 IMP palate development
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060197 IEP cloacal septation
GO:0060412 IEA ventricular septum morphogenesis
GO:0060484 IEP lung-associated mesenchyme development
GO:0060548 IMP negative regulation of cell death
GO:0060675 IEP ureteric bud morphogenesis
GO:0061037 NAS negative regulation of cartilage development
GO:0061101 IMP neuroendocrine cell differentiation
GO:0070830 IEA tight junction assembly
GO:0071300 ISS cellular response to retinoic acid
GO:0072177 IEP mesonephric duct development
GO:0072201 IEA negative regulation of mesenchymal cell proliferation
GO:0090037 IMP positive regulation of protein kinase C signaling
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0090272 IEA negative regulation of fibroblast growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014796 wnt11r wingless-type MMTV integration site family, member 11, related protein_coding Danio_rerio
ENSMUSG00000015957 Wnt11 wingless-type MMTV integration site family, member 11 protein_coding Mus_musculus

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