C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015957 Wnt11 10090 + 7:98835112-98855195 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067495 Wnt11-001 98835131-98855195 protein_coding
  ENSMUST00000163913 Wnt11-003 98835112-98853811 nonsense_mediated_decay
  ENSMUST00000165122 Wnt11-005 98835112-98846587 protein_coding
  ENSMUST00000165240 Wnt11-004 98838898-98853571 nonsense_mediated_decay
  ENSMUST00000167303 Wnt11-002 98838845-98853751 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067495ENSMUST00000163913ENSMUST00000165122ENSMUST00000165240ENSMUST00000167303
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067495 N/A 0.280±0.09 N/A N/A 1.103±0.00 0.196±0.07 N/A 0.154±0.01 N/A N/A 0.159±0.06 2.438±0.40 0.064±0.00 N/A
ENSMUST00000163913 N/A 0.420±0.20 N/A 0.322±0.00 0.928±0.00 0.214±0.00 N/A 0.222±0.00 0.143±0.03 N/A 1.318±0.20 2.824±0.27 1.027±0.37 N/A
ENSMUST00000165122 5.775±0.16 1.991±0.72 N/A N/A 7.917±2.45 1.096±0.21 N/A 1.937±0.45 0.086±0.03 6.994±1.72 N/A 17.895±3.56 0.892±0.00 0.358±0.00
ENSMUST00000165240 2.425±0.11 0.587±0.23 1.611±0.13 0.505±0.15 3.880±1.71 0.925±0.27 1.004±0.45 0.811±0.29 0.165±0.13 3.458±1.18 N/A 11.314±5.21 0.716±0.39 0.214±0.16
ENSMUST00000167303 1.827±0.17 0.377±0.16 2.807±1.01 0.632±0.05 2.686±0.00 0.450±0.12 1.338±0.46 0.864±0.21 0.322±0.21 2.525±0.47 1.360±0.52 4.479±2.00 0.783±0.20 0.122±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000927 CIL_000927_0002 VISTA 7:98656508-99258633
CIL_0001HX CIL_0001HX_0002 CGP 7:98835112-99141144

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IGI osteoblast differentiation
GO:0001822 IDA kidney development
GO:0003151 IMP outflow tract morphogenesis
GO:0005099 ISS Ras GTPase activator activity
GO:0005102 TAS receptor binding
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 IDA:ISS cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0009887 TAS organ morphogenesis
GO:0010628 ISS positive regulation of gene expression
GO:0030154 IEA cell differentiation
GO:0030182 IBA neuron differentiation
GO:0030282 IGI bone mineralization
GO:0030295 ISS protein kinase activator activity
GO:0030308 ISS negative regulation of cell growth
GO:0030325 IEA adrenal gland development
GO:0030335 ISS positive regulation of cell migration
GO:0030336 ISS negative regulation of cell migration
GO:0031012 IDA extracellular matrix
GO:0031667 IEA response to nutrient levels
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0032915 IMP positive regulation of transforming growth factor beta2 production
GO:0034394 ISS protein localization to cell surface
GO:0035567 IMP non-canonical Wnt signaling pathway
GO:0043065 IMP positive regulation of apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045165 IBA cell fate commitment
GO:0045860 IEA positive regulation of protein kinase activity
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048706 IEA embryonic skeletal system development
GO:0048844 IMP artery morphogenesis
GO:0051496 ISS positive regulation of stress fiber assembly
GO:0060021 IMP:ISS palate development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060197 IEA cloacal septation
GO:0060412 IMP ventricular septum morphogenesis
GO:0060484 IEA lung-associated mesenchyme development
GO:0060548 ISS negative regulation of cell death
GO:0060675 IEA ureteric bud morphogenesis
GO:0061101 ISS neuroendocrine cell differentiation
GO:0070830 IMP tight junction assembly
GO:0072177 IEA mesonephric duct development
GO:0072201 IMP negative regulation of mesenchymal cell proliferation
GO:0090037 ISS positive regulation of protein kinase C signaling
GO:0090090 IDA:ISS negative regulation of canonical Wnt signaling pathway
GO:0090272 IMP negative regulation of fibroblast growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014796 wnt11r wingless-type MMTV integration site family, member 11, related protein_coding Danio_rerio
ENSG00000085741 WNT11 wingless-type MMTV integration site family, member 11 protein_coding Homo_sapiens

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