Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	origin recognition complex, subunit 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000085840	ORC1	9606	-	1:52372829-52404459	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000371566		ORC1-002	52372831-52404387	protein_coding
	ENST00000371568		ORC1-001	52372829-52404459	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000371566	N/A	1.164±0.00	0.106±0.00	0.010±0.00	0.227±0.00	0.121±0.01	N/A	0.222±0.08	0.083±0.02	0.265±0.12	0.047±0.00	0.303±0.00	1.114±0.56	0.305±0.00
ENST00000371568	0.166±0.00	N/A	N/A	0.088±0.09	0.183±0.00	0.708±0.00	0.103±0.00	N/A	N/A	N/A	N/A	1.513±1.09	1.407±0.65	2.351±1.19

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000082	TAS	G1/S transition of mitotic cell cycle
GO:0000083	TAS	regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000278	TAS	mitotic cell cycle
GO:0000808	IDA	origin recognition complex
GO:0003677	IEA	DNA binding
GO:0003682	IEA	chromatin binding
GO:0005515	IPI	protein binding
GO:0005524	IEA	ATP binding
GO:0005634	IDA	nucleus
GO:0005654	TAS	nucleoplasm
GO:0005664	IDA	nuclear origin of replication recognition complex
GO:0005730	IDA	nucleolus
GO:0005737	IDA	cytoplasm
GO:0005829	TAS	cytosol
GO:0005886	IDA	plasma membrane
GO:0006260	TAS	DNA replication
GO:0006270	TAS	DNA replication initiation

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000039217	orc1	origin recognition complex, subunit 1	protein_coding	Danio_rerio
ENSMUSG00000028587	Orc1	origin recognition complex, subunit 1	protein_coding	Mus_musculus

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