C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol-trisphosphate 3-kinase C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000086544 ITPKC 9606 + 19:40717103-40740860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263370 ITPKC-001 40717103-40740860 protein_coding
  ENST00000597003 ITPKC-002 40729321-40739669 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263370
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263370 22.636±0.00 24.219±0.00 0.724±0.00 7.578±6.56 7.798±2.74 7.787±6.24 3.966±3.58 7.253±6.46 4.316±1.60 20.157±17.08 3.483±2.78 14.819±10.38 18.791±1.16 9.179±2.71

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0008440 IEA inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002994 itpkca inositol 1,4,5-trisphosphate 3-kinase Ca protein_coding Danio_rerio
ENSDARG00000067741 itpkcb inositol 1,4,5-trisphosphate 3-kinase Cb protein_coding Danio_rerio
ENSMUSG00000003752 Itpkc inositol 1,4,5-trisphosphate 3-kinase C protein_coding Mus_musculus

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