Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	inositol 1,4,5-trisphosphate 3-kinase C
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000003752	Itpkc	10090	-	7:27207172-27228628	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000003850		Itpkc-001	27207172-27228628	protein_coding
	ENSMUST00000147170		Itpkc-003	27207970-27213052	processed_transcript
	ENSMUST00000149067		Itpkc-002	27212565-27214454	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000003850	4.216±1.47	5.711±1.39	5.259±0.27	4.308±1.23	3.679±1.58	9.487±0.85	1.641±0.20	2.727±0.62	1.699±0.38	4.105±0.79	1.715±0.34	4.797±1.26	3.870±1.38	2.444±0.95
ENSMUST00000147170	N/A	N/A	N/A	N/A	N/A	N/A	N/A	2.351±0.00	2.850±0.09	N/A	N/A	7.450±0.00	N/A	2.092±0.00
ENSMUST00000149067	N/A	N/A	N/A	3.906±0.00	N/A	N/A	N/A	N/A	N/A	N/A	N/A	6.759±0.00	3.633±0.59	1.734±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0006UT	CIL_0006UT_0002	CGP	7:27195781-27228628

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005515	IPI	protein binding
GO:0005516	IEA	calmodulin binding
GO:0005524	IEA	ATP binding
GO:0005575	ND	cellular_component
GO:0005634	IEA	nucleus
GO:0005737	IEA	cytoplasm
GO:0008440	IDA	inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016301	IEA	kinase activity
GO:0016310	IEA	phosphorylation

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000002994	itpkca	inositol 1,4,5-trisphosphate 3-kinase Ca	protein_coding	Danio_rerio
ENSDARG00000067741	itpkcb	inositol 1,4,5-trisphosphate 3-kinase Cb	protein_coding	Danio_rerio
ENSG00000086544	ITPKC	inositol-trisphosphate 3-kinase C	protein_coding	Homo_sapiens

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