C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000089060 SLC8B1 9606 - 12:113298759-113359493 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000202831 SLC8B1-201 113298767-113335120 protein_coding
  ENST00000546737 SLC8B1-002 113299777-113332947 protein_coding
  ENST00000548186 SLC8B1-014 113320876-113335119 protein_coding
  ENST00000548477 SLC8B1-003 113319974-113335143 retained_intron
  ENST00000548518 SLC8B1-009 113334672-113359466 processed_transcript
  ENST00000549069 SLC8B1-011 113299332-113306844 protein_coding
  ENST00000549181 SLC8B1-015 113320331-113335141 protein_coding
  ENST00000549372 SLC8B1-008 113321196-113359493 protein_coding
  ENST00000549605 SLC8B1-012 113320361-113335122 nonsense_mediated_decay
  ENST00000550047 SLC8B1-006 113298781-113308843 protein_coding
  ENST00000550672 SLC8B1-007 113298777-113320878 nonsense_mediated_decay
  ENST00000551230 SLC8B1-010 113315342-113335107 processed_transcript
  ENST00000552014 SLC8B1-001 113298759-113335030 protein_coding
  ENST00000552565 SLC8B1-005 113298773-113319325 retained_intron
  ENST00000552613 SLC8B1-013 113320850-113334613 nonsense_mediated_decay
  ENST00000553238 SLC8B1-004 113307800-113334833 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000202831ENST00000548186ENST00000548477ENST00000549605ENST00000550047ENST00000550672ENST00000551230ENST00000552014ENST00000552565ENST00000552613ENST00000553238
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000202831 N/A N/A N/A N/A 4.975±0.00 N/A N/A 4.558±0.00 1.739±0.00 N/A 0.829±0.00 14.339±0.00 1.471±0.00 3.503±0.47
ENST00000548186 N/A N/A N/A N/A 3.112±0.00 3.828±0.00 N/A 0.997±0.00 N/A 2.751±0.00 N/A 6.949±0.00 N/A N/A
ENST00000548477 N/A N/A 0.491±0.00 1.871±0.00 N/A N/A N/A 0.537±0.00 N/A 1.951±0.00 N/A 1.725±0.00 N/A N/A
ENST00000549605 N/A N/A N/A 0.982±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000550047 N/A 2.096±0.00 N/A 0.864±0.00 N/A N/A N/A N/A N/A N/A N/A 3.237±0.00 N/A N/A
ENST00000550672 N/A N/A N/A N/A N/A 0.394±0.00 N/A N/A N/A N/A 0.473±0.00 N/A N/A N/A
ENST00000551230 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.337±0.00 N/A N/A
ENST00000552014 N/A N/A 0.520±0.00 2.053±0.00 N/A 0.774±0.00 1.251±0.00 N/A 3.126±0.00 N/A N/A 11.950±8.15 4.415±1.93 4.684±0.00
ENST00000552565 N/A 3.222±0.00 N/A N/A N/A N/A 0.729±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000552613 10.776±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.963±0.00 12.814±0.00 12.389±0.00
ENST00000553238 N/A N/A N/A N/A N/A N/A N/A 0.742±0.00 N/A 2.562±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005432 IMP calcium:sodium antiporter activity
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005886 TAS plasma membrane
GO:0006811 TAS ion transport
GO:0006851 IMP mitochondrial calcium ion transport
GO:0016021 IEA integral component of membrane
GO:0030061 IDA mitochondrial crista
GO:0032592 IDA integral component of mitochondrial membrane
GO:0035725 IEA sodium ion transmembrane transport
GO:0042383 IEA sarcolemma
GO:0042593 IDA glucose homeostasis
GO:0042803 IPI protein homodimerization activity
GO:0050796 IDA regulation of insulin secretion
GO:0050896 IEA response to stimulus
GO:0051480 IMP cytosolic calcium ion homeostasis
GO:0051560 IMP mitochondrial calcium ion homeostasis
GO:0055085 TAS:IEA transmembrane transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0086036 TAS regulation of cardiac muscle cell membrane potential
GO:0086038 TAS calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086905 FP103011.3 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000032754 Slc8b1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 protein_coding Mus_musculus

Loading