C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090020 SLC9A1 9606 - 1:27098815-27166981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263980 SLC9A1-001 27098815-27154910 protein_coding
  ENST00000374084 SLC9A1-004 27114233-27166981 protein_coding
  ENST00000374086 SLC9A1-002 27105451-27154598 protein_coding
  ENST00000374089 SLC9A1-003 27098815-27104022 retained_intron
  ENST00000447808 SLC9A1-005 27100345-27102795 retained_intron
  ENST00000490329 SLC9A1-006 27098816-27099682 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263980ENST00000374084ENST00000374086ENST00000374089ENST00000447808ENST00000490329
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263980 6.657±0.00 6.019±0.00 3.994±2.61 4.170±2.59 5.770±1.39 1.612±1.27 3.427±3.30 0.481±0.00 6.465±5.46 2.314±0.00 9.871±3.61 27.823±8.55 4.163±2.42
ENST00000374084 N/A N/A N/A N/A N/A N/A N/A N/A 1.559±0.00 N/A N/A N/A N/A
ENST00000374086 N/A N/A N/A N/A N/A N/A 0.186±0.00 0.360±0.00 0.783±0.00 N/A 0.603±0.00 N/A N/A
ENST00000374089 N/A N/A N/A 0.206±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000447808 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.526±0.00 N/A N/A
ENST00000490329 N/A N/A 9.310±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IEA regulation of the force of heart contraction
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 ISS endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0005975 TAS carbohydrate metabolic process
GO:0006811 TAS ion transport
GO:0006812 IEA cation transport
GO:0006814 IEA sodium ion transport
GO:0006885 TAS:IEA regulation of pH
GO:0009986 IEA cell surface
GO:0010447 IDA response to acidic pH
GO:0014070 IEA response to organic cyclic compound
GO:0014704 IEA intercalated disc
GO:0015299 TAS:IEA solute:proton antiporter activity
GO:0015385 ISS:IEA sodium:proton antiporter activity
GO:0016020 IEA membrane
GO:0016021 IEA:TAS integral component of membrane
GO:0016049 IEA cell growth
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0030154 IEA cell differentiation
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030212 TAS hyaluronan metabolic process
GO:0030214 TAS hyaluronan catabolic process
GO:0030307 IEA positive regulation of cell growth
GO:0030315 IEA T-tubule
GO:0032869 IEA cellular response to insulin stimulus
GO:0035725 IEA sodium ion transmembrane transport
GO:0035794 IEA positive regulation of mitochondrial membrane permeability
GO:0042383 IEA sarcolemma
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0045121 IEA membrane raft
GO:0045760 IEA positive regulation of action potential
GO:0048306 IDA calcium-dependent protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051259 ISS protein oligomerization
GO:0051453 IDA regulation of intracellular pH
GO:0051930 IEA regulation of sensory perception of pain
GO:0055007 IEA cardiac muscle cell differentiation
GO:0055085 TAS:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0070997 IEA neuron death
GO:0071236 IEA cellular response to antibiotic
GO:0071257 IEA cellular response to electrical stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071436 ISS sodium ion export
GO:0071456 IEA cellular response to hypoxia
GO:0071468 ISS cellular response to acidic pH
GO:0086003 IEA cardiac muscle cell contraction
GO:1902533 IEA positive regulation of intracellular signal transduction
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067784 SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 protein_coding Danio_rerio
ENSMUSG00000028854 Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 protein_coding Mus_musculus

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