C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 9 (sodium/hydrogen exchanger), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028854 Slc9a1 10090 + 4:133369706-133423702 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030669 Slc9a1-001 133369706-133423702 protein_coding
  ENSMUST00000132864 Slc9a1-004 133419481-133420165 processed_transcript
  ENSMUST00000140681 Slc9a1-002 133370644-133412136 processed_transcript
  ENSMUST00000141658 Slc9a1-005 133419972-133422320 processed_transcript
  ENSMUST00000156079 Slc9a1-003 133416306-133420555 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030669 11.680±1.65 24.778±8.15 14.334±1.87 6.644±1.41 16.276±4.76 23.158±1.13 5.747±1.18 9.858±1.10 3.370±1.81 14.732±1.76 3.006±0.45 17.274±3.90 8.420±4.11 15.325±7.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WN CIL_0008WN_0002 VISTA 4:132816592-133418424

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IEA regulation of the force of heart contraction
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 ISS endoplasmic reticulum
GO:0005886 ISS plasma membrane
GO:0005925 IEA focal adhesion
GO:0006814 IDA sodium ion transport
GO:0006885 IDA regulation of pH
GO:0009986 IEA cell surface
GO:0010447 IMP response to acidic pH
GO:0014070 IEA response to organic cyclic compound
GO:0014704 IEA intercalated disc
GO:0015385 IDA sodium:proton antiporter activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IEA cell growth
GO:0016323 TAS basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0030154 IEA cell differentiation
GO:0030307 IEA positive regulation of cell growth
GO:0030315 IEA T-tubule
GO:0032869 IEA cellular response to insulin stimulus
GO:0035794 IEA positive regulation of mitochondrial membrane permeability
GO:0042383 IEA sarcolemma
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0045121 IEA membrane raft
GO:0045760 IEA positive regulation of action potential
GO:0048306 IEA calcium-dependent protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051259 ISS protein oligomerization
GO:0051453 IEA regulation of intracellular pH
GO:0051930 IEA regulation of sensory perception of pain
GO:0055007 IMP cardiac muscle cell differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0070997 IEA neuron death
GO:0071236 IEA cellular response to antibiotic
GO:0071257 IEA cellular response to electrical stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071436 ISS sodium ion export
GO:0071456 IEA cellular response to hypoxia
GO:0071468 ISS cellular response to acidic pH
GO:0086003 IEA cardiac muscle cell contraction
GO:1902533 IEA positive regulation of intracellular signal transduction
GO:1902600 IEA hydrogen ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067784 SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 protein_coding Danio_rerio
ENSG00000090020 SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 protein_coding Homo_sapiens

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