C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: intercellular adhesion molecule 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090339 ICAM1 9606 + 19:10270835-10286615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264832 ICAM1-001 10270835-10286615 protein_coding
  ENST00000423829 ICAM1-002 10271093-10285583 protein_coding
  ENST00000585443 ICAM1-005 10282258-10283586 processed_transcript
  ENST00000588645 ICAM1-004 10271120-10283753 protein_coding
  ENST00000592686 ICAM1-006 10283282-10284098 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264832ENST00000423829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264832 N/A N/A N/A N/A 2.538±1.31 0.930±0.00 2.898±0.00 N/A 2.767±0.00 8.015±0.00 N/A 7.732±4.99 8.586±2.10 1.673±0.00
ENST00000423829 10.526±0.00 40.117±0.00 2.750±0.00 1.600±0.00 8.106±1.82 5.927±2.64 1.560±0.00 3.284±0.00 3.899±0.00 131.381±114.97 1.243±0.00 N/A 11.795±0.00 4.647±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004G9 CIL_0004G9_0001 CGP 19:10251901-10286615
CIL_0004GF CIL_0004GF_0001 CGP 19:10270835-10288522

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0001618 IEA virus receptor activity
GO:0001666 IEA response to hypoxia
GO:0001772 IEA immunological synapse
GO:0001910 TAS regulation of leukocyte mediated cytotoxicity
GO:0001975 IEA response to amphetamine
GO:0002291 IMP T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
GO:0002438 IEA acute inflammatory response to antigenic stimulus
GO:0002457 IEA T cell antigen processing and presentation
GO:0002693 IMP positive regulation of cellular extravasation
GO:0004872 TAS receptor activity
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IDA focal adhesion
GO:0007155 IDA cell adhesion
GO:0007157 TAS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0007569 IEA cell aging
GO:0007605 IEA sensory perception of sound
GO:0008360 IEA regulation of cell shape
GO:0009615 IEA response to virus
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010212 IEA response to ionizing radiation
GO:0010477 IEA response to sulfur dioxide
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IDA membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0022614 IEP membrane to membrane docking
GO:0030155 IEA regulation of cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031669 IEA cellular response to nutrient levels
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032403 IEA protein complex binding
GO:0032496 IEA response to lipopolysaccharide
GO:0033627 IEA cell adhesion mediated by integrin
GO:0034698 IEA response to gonadotropin
GO:0042493 IEA response to drug
GO:0043200 IEA response to amino acid
GO:0044406 IDA adhesion of symbiont to host
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045471 IEA response to ethanol
GO:0045907 IEA positive regulation of vasoconstriction
GO:0046688 IEA response to copper ion
GO:0046813 IDA receptor-mediated virion attachment to host cell
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050776 TAS regulation of immune response
GO:0050900 IEP leukocyte migration
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0051926 IEA negative regulation of calcium ion transport
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0061028 IGI establishment of endothelial barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071310 IEA cellular response to organic substance
GO:0071312 IEA cellular response to alkaloid
GO:0071333 IEA cellular response to glucose stimulus
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071456 IEA cellular response to hypoxia
GO:0097368 IEA establishment of Sertoli cell barrier
GO:1900027 IEA regulation of ruffle assembly
GO:1902042 IDA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000352 IDA negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037405 Icam1 intercellular adhesion molecule 1 protein_coding Mus_musculus

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