C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light chain 6, alkali, smooth muscle and non-muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092841 MYL6 9606 + 12:56158161-56163496 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293422 MYL6-023 56158356-56161574 protein_coding
  ENST00000348108 MYL6-024 56158356-56161587 protein_coding
  ENST00000536128 MYL6-005 56158362-56160795 protein_coding
  ENST00000546630 MYL6-021 56158373-56159791 retained_intron
  ENST00000546845 MYL6-009 56160036-56162970 nonsense_mediated_decay
  ENST00000547408 MYL6-007 56158368-56163008 protein_coding
  ENST00000547649 MYL6-002 56158362-56161574 protein_coding
  ENST00000547703 MYL6-012 56158358-56160280 retained_intron
  ENST00000548293 MYL6-010 56158396-56160945 protein_coding
  ENST00000548400 MYL6-018 56158382-56161575 protein_coding
  ENST00000548580 MYL6-014 56158346-56161575 protein_coding
  ENST00000548725 MYL6-015 56158364-56160343 retained_intron
  ENST00000549017 MYL6-025 56158357-56161574 protein_coding
  ENST00000549392 MYL6-022 56158382-56160320 protein_coding
  ENST00000549566 MYL6-013 56158358-56161465 protein_coding
  ENST00000550184 MYL6-004 56158349-56161550 retained_intron
  ENST00000550639 MYL6-017 56158371-56160148 processed_transcript
  ENST00000550697 MYL6-003 56158161-56161574 protein_coding
  ENST00000551589 MYL6-001 56158369-56161298 protein_coding
  ENST00000551954 MYL6-008 56161781-56163496 processed_transcript
  ENST00000552297 MYL6-016 56158356-56160320 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348108ENST00000547649ENST00000548293ENST00000548400ENST00000549017ENST00000549392ENST00000550639
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348108 N/A N/A N/A 113.295±0.00 431.500±0.00 N/A 55.799±41.20 N/A 64.602±0.00 372.506±0.00 N/A 794.488±236.15 1192.260±252.41 495.573±0.00
ENST00000547649 258.896±0.00 307.383±0.00 30.466±0.00 59.123±0.00 118.905±0.00 448.185±263.45 76.721±52.18 437.060±337.83 233.364±48.04 535.893±409.31 41.414±0.00 522.279±297.30 844.283±179.91 N/A
ENST00000548293 N/A N/A 18.671±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000548400 589.798±0.00 597.287±0.00 N/A 157.093±0.00 974.943±0.00 1090.810±0.00 N/A 686.580±0.00 136.432±0.00 754.453±0.00 N/A N/A 540.849±0.00 793.015±0.00
ENST00000549017 287.614±0.00 300.282±0.00 N/A N/A N/A 434.610±0.00 N/A N/A N/A N/A N/A 667.355±0.00 N/A N/A
ENST00000549392 N/A 424.062±0.00 N/A 124.755±0.00 116.316±0.00 449.702±247.61 N/A 138.118±0.00 298.375±0.00 128.395±0.00 64.742±0.00 732.217±584.25 1588.140±0.00 645.307±0.00
ENST00000550639 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1559.000±0.00 1172.900±0.00 641.945±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003774 TAS motor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0006200 ISS ATP catabolic process
GO:0006936 TAS muscle contraction
GO:0007411 TAS axon guidance
GO:0007519 TAS skeletal muscle tissue development
GO:0008152 TAS metabolic process
GO:0008307 IDA structural constituent of muscle
GO:0016020 IDA membrane
GO:0016459 TAS myosin complex
GO:0016461 TAS unconventional myosin complex
GO:0030049 TAS muscle filament sliding
GO:0030898 ISS actin-dependent ATPase activity
GO:0031982 IDA vesicle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008494 myl6 myosin, light chain 6, alkali, smooth muscle and non-muscle protein_coding Danio_rerio
ENSDARG00000033738 zgc:153867 zgc:153867 protein_coding Danio_rerio
ENSMUSG00000090841 Myl6 myosin, light polypeptide 6, alkali, smooth muscle and non-muscle protein_coding Mus_musculus

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