C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099377 HSD3B7 9606 + 16:30985207-30989152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262520 HSD3B7-002 30985207-30989146 protein_coding
  ENST00000297679 HSD3B7-001 30985211-30989152 protein_coding
  ENST00000562932 HSD3B7-003 30985215-30986707 protein_coding
  ENST00000574447 HSD3B7-004 30985216-30986703 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000297679
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000297679 5.317±0.00 14.276±0.00 18.421±0.00 2.155±1.05 1.509±1.21 12.810±7.31 34.133±0.00 3.217±0.00 8.996±6.00 6.309±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044U CIL_00044U_0002 CGP 16:30957294-30989152
CIL_0001X8 CIL_0001X8_0001 CGP 16:30985207-31010628

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003854 IEA:NAS 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0005575 ND cellular_component
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006694 IEA steroid biosynthetic process
GO:0006699 TAS bile acid biosynthetic process
GO:0008152 IEA metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0009058 IEA biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044281 TAS small molecule metabolic process
GO:0047016 IEA cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
GO:0050662 IEA coenzyme binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036966 hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase protein_coding Danio_rerio
ENSMUSG00000042289 Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 protein_coding Mus_musculus

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